footprintDB - a database of transcription factors with annotated cis elements (DNA motifs and sites) and binding interfaces

DNA Binding Site

Accessions:	en_37-1-B (DrosophilaTF 1.1), TAATTAAA (UniPROBE 20160601)
Organisms:	Drosophila melanogaster, Mus musculus, Saccharomyces cerevisiae, Homo sapiens
Libraries:	DrosophilaTF 1.1 ¹, UniPROBE 20160601 ² ¹ Down T.A, Bergman C.M, Su J, Hubbard T.J. Large-scale discovery of promoter motifs in Drosophila melanogaster. PLoS computational biology 3:e7 (2007). [Pubmed] ² Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed]
Length:	8
Sequence:	TAATTAAA
Type:	Heterodimer
Binding TFs:	UP00127A (Homeobox domain) en (Homeobox domain, Engrailed homeobox C-terminal signature domain) UP00235A (Homeobox domain, Protein of unknown function (DUF3528)) UP00063A / UP00391A (Homeobox domain) UP00078A (ARID/BRIGHT DNA binding domain) UP00105A (Homeobox domain, Pou domain - N-terminal to homeobox domain) UP00106A (Homeobox domain) UP00108A (Homeobox domain) UP00110A (Homeobox domain) UP00115A (Homeobox domain, Homeobox KN domain) UP00116A (Homeobox domain) UP00118A (Homeobox domain, Pou domain - N-terminal to homeobox domain) UP00120A (Homeobox domain) UP00121A (Homeobox domain) UP00126A (Homeobox domain) UP00128A (Homeobox domain, Pou domain - N-terminal to homeobox domain) UP00129A (Homeobox domain, Pou domain - N-terminal to homeobox domain) UP00130A (Homeobox domain, Homeobox KN domain) UP00135A (Homeobox domain) UP00136A (Homeobox domain, Homeobox KN domain) UP00140A (Homeobox domain) UP00141A (Homeobox domain) UP00142A (Homeobox domain) UP00144A (Homeobox domain) UP00152A (Homeobox domain) UP00154A (Homeobox domain) UP00158A (Homeobox domain, Pou domain - N-terminal to homeobox domain) UP00169A (Homeobox domain, Homeobox KN domain) UP00172A (Homeobox domain, Homeobox KN domain) UP00175A (Homeobox domain, Homeobox KN domain) UP00177A (Homeobox domain) UP00178A (Homeobox domain) UP00187A (Homeobox domain) UP00188A (Homeobox domain, Homeobox KN domain) UP00191A (Homeobox domain, Pou domain - N-terminal to homeobox domain) UP00196A (Homeobox domain) UP00200A (Homeobox domain) UP00201A (Homeobox domain) UP00202A (Homeobox domain) UP00207A (Homeobox domain) UP00212A (Homeobox domain, Homeobox KN domain) UP00217A (Homeobox domain) UP00218A (Homeobox domain) UP00233A (Homeobox domain) UP00237A (Homeobox domain) UP00238A (Homeobox domain) UP00240A (Homeobox domain) UP00246A (Homeobox domain) UP00247A (Homeobox domain, 'Paired box' domain) UP00251A (Homeobox domain) UP00252A (Homeobox domain) UP00253A (Homeobox domain) UP00257A (Homeobox domain) UP00260A (Homeobox domain) UP00262A (Homeobox domain, Homeobox KN domain) UP00264A (Homeobox domain) UP00266A (Homeobox domain) UP00268A (Homeobox domain) UP00274A (Homeobox domain) UP00164A (Homeobox domain) UP00209A (Homeobox domain, Homeobox KN domain) UP00256A (Homeobox domain, Homeobox KN domain) UP00503A (Homeobox domain) UP00510A (Homeobox domain) UP00584A (Homeobox domain) UP00584E (Homeobox domain) UP00584F (Homeobox domain) UP00594A (Homeobox domain) UP00594C (Homeobox domain) UP00596B (Homeobox domain) UP00596C (Homeobox domain) UP00597D (Homeobox domain) UP00598A (Homeobox domain) UP00598B (Homeobox domain) UP00603A (Homeobox domain) UP00603B (Homeobox domain) UP00603C (Homeobox domain) UP00610A (Homeobox domain, 'Paired box' domain) UP00610B (Homeobox domain, 'Paired box' domain) UP00610C (Homeobox domain, 'Paired box' domain) UP00610D (Homeobox domain, 'Paired box' domain) UP00613B (Homeobox domain, Homeobox KN domain) UP00616A (Homeobox domain, Pou domain - N-terminal to homeobox domain) UP00616B (Homeobox domain, Pou domain - N-terminal to homeobox domain) UP00616C (Homeobox domain, Pou domain - N-terminal to homeobox domain) UP00616E (Homeobox domain, Pou domain - N-terminal to homeobox domain) UP00618A (Homeobox domain, Pou domain - N-terminal to homeobox domain) UP00619A (Homeobox domain, Homeobox KN domain) UP00623A (Homeobox domain) UP00626A (Homeobox domain) UP00626C (Homeobox domain)
Binding Motifs:	UP00200A_2 rrtwATTAATKAykyc UP00063A_1 tkgagbTAATTAry UP00078A_1 sgktTTAATTAAwmtwy UP00105A_1 rmttAATTAATTAadtc UP00106A_1 kwvcryTAATTArkrc UP00108A_1 wawayTAATTAryTsav UP00110A_1 bcrcdaTAATTAcmswc UP00115A_1 waaayTAATTArykmhs UP00116A_1 wrcmyTAATTArtkswy UP00140A_2 ywarGTCGTAAAawyht UP00118A_1 wrtwATTAATkArkyc UP00120A_1 tgmayYAATTRryksrr UP00121A_1 / UP00140A_1 mrkgyAATAAAAtwwww UP00126A_1 vrdrYAATTRbhymag UP00127A_1 asryTAATTAgyysAk UP00128A_1 swtAaTTAATTArkkyr UP00129A_1 rmyTAATTAATTAaktm UP00130A_1 sdaaTTAATTAAwwmmk UP00135A_1 ywrgGTCGTAAAwwywc UP00136A_1 wvmrYTAATTARygrwr UP00140A_5 wraryTAATTArytgkw UP00141A_1 csaryTAATTAryratt UP00142A_1 vataaTTAATTAAygsg UP00144A_1 cgmrTTAATTAAtwahy UP00152A_1 gtscryTAATTArtksw UP00154A_1 kmrmdaTAATTAcmswm UP00158A_1 rrwtAATTAATTAwgtc UP00164A_1 sgmrtTAATTAatwagc UP00169A_1 rrwwwTTAATTAAtwyb UP00172A_1 cgmrTTAATTAAkwdac UP00175A_1 csyayTAATTArtymcy UP00140A_3 / UP00177A_1 ywavGTCGTAAAatywt UP00178A_1 cgsryyAATTrrkways UP00140A_4 mwwyyAATAAAAhymh UP00264A_3 wwwbCTCGTAAAawtt UP00187A_1 cgcryTAATTArthasc UP00188A_1 sgawTTAATTAAwwwyy UP00191A_1 ywkTATGCWAATkara UP00196A_1 grttrtTAATTAackbg UP00200A_1 gmwwATTAATTAmyybg UP00201A_1 wvmrCTAATTAGykshy UP00202A_1 btgarrTAATTAay UP00207A_1 rrrgymATWAAAwycr UP00209A_1 cgmryTAATTArtymcy UP00212A_1 sraaTTAATTAAwwamy UP00217A_1 / UP00264A_1 dmgGyMATWAAAtkmw UP00218A_1 bktmAtTAATkAakwm UP00233A_1 rvkgTAATTAsmycAg UP00235A_1 yaarGTCGTAAAayrk UP00237A_1 cryarTTAATTAAykkg UP00238A_1 gawwwTTAATKAmtkyk UP00240A_1 wrmGGYmATWAAatkw UP00246A_1 / UP00264A_2 waarGTCRTAAAayrk UP00247A_1 wsawyTAATTAryysdm UP00251A_1 wwycryTAATTArtksw UP00252A_1 cgmrtTAATTAatwayt UP00253A_1 wscayYAATTRryssmy UP00256A_1 swrcryTAATTArkkyw UP00257A_1 ckmsyTAATTArtyrds UP00260A_1 yrarkTAATTAmtwamw UP00262A_1 mgwaTTAATTAAwwahk UP00264A_4 ctrarcTAATTAmyky UP00266A_1 vkaayTAATTAryTast UP00268A_1 cgyddwtTAATTAawksgrm UP00274A_1 ttsmmaYTAATTARwwwmks UP00391A_1 tygmrbTAATTAry en TAATTa UP00063A_2 aarawCbATTArsr UP00078A_2 hmmvrtATcrdrtyk UP00164A_2 kkmkTAATTAmkggmm UP00209A_2 crmrTTAATTAAttgrm UP00256A_2 wmcrCTAATTAGcggwk UP00503A_1 ggrarrgGymATWAAattyhba UP00510A_1 myacTgrrcTAATTAscsbrdr UP00584A_1 trhatvsyTAATTArktwtmtt UP00584E_1 tkacggwtTAATTAatywtckk UP00584F_1 amgatrayTAATTArygsbgcm UP00594A_1 gkscscryTAATTArymmgcgg UP00594C_1 kkycscryTAATTArtmakcsg UP00596B_1 kkmcgcgTTAATTAAkmmtcgr UP00596B_2 twmmwasyTAATTArtwawadk UP00596C_1 kkcsrmgtTAATTAakmatcgg UP00597D_1 tkswwyyyaATAAAAwwcmmtt UP00598A_1 mctwkrsCTAATTAGagcmssg UP00598B_1 ykyrscmYTAATTAAkmwsckg UP00598B_2 gkcmscryTAATTArkvhkssb UP00603A_1 mtwyaaaAAcCAATTAacwmray UP00603B_1 wtwtrtgyAATTAwttaaktysw UP00603C_1 awwsydrACYAATTAdsgcmdy UP00603C_2 ydmmayrCyAATTrGtmwtyrs UP00610A_1 kywsrksskCTAATTArkgcwmT UP00610A_2 aAkwrccyTAATTArmhsmhbw UP00610A_3 wwkrmycaATTAATtwgkkcdc UP00610B_1 twwwkcbkttTAATTAasmasgk UP00610C_1 aakwsswyTAATTArygsacbw UP00610C_2 aakwgswyTAATTArygsacbw UP00610D_1 varwsgcytAATTarkccmwwk UP00610D_2 aakwgshyTAATTArygsackw UP00613B_1 aakrbywcTAATTAgwrcymsh UP00613B_2 ykwmrwctTAATTAaratysrr UP00616A_1 ykwrytwATTATGCAkaywkhm UP00616B_1 hkwrythATTATGCRgayakhm UP00616C_1 kgacgyyyTAATTArwcrtcrr UP00616E_1 kgmcgyyyTAATTArwcakcrg UP00618A_1 wwvrybagcTAATTArkgywmt UP00619A_1 wAytkTAATywAATTAkyTdag UP00623A_1 tyatcggsTAATTAscycAktmr UP00626A_1 wtmcryrYTAATTARkrrwgrg UP00626C_1 tmmmamvTTAATTAAkwrtmtg
Publications:	Ades S.E, Sauer R.T. Differential DNA-binding specificity of the engrailed homeodomain: the role of residue 50. Biochemistry 33:9187-94 (1994). [Pubmed] Badis G, Berger M.F, Philippakis A.A, Talukder S, Gehrke A.R, Jaeger S.A, Chan E.T, Metzler G, Vedenko A, Chen X, Kuznetsov H, Wang C.F, Coburn D, Newburger D.E, Morris Q, Hughes T.R, Bulyk M.L. Diversity and complexity in DNA recognition by transcription factors. Science (New York, N.Y.) 324:1720-3 (2009). [Pubmed]

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.

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