Transcription Factor
| Accessions: | UP00510A (UniPROBE 20160601) |
| Names: | CG6534, Dmel\CG6534, Homeobox protein NK-1, Homeobox protein slou, Nk1, NK1/S59, prd9, Protein slouch, S-59, S59/2, S59/NK-1, Slou, slou/NK1, Slouch |
| Organisms: | Drosophila melanogaster |
| Libraries: | UniPROBE 20160601 1 1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed] |
| Description: | Slouch: Slou may play a role in specifying the identity of particular somatic muscles and neurons of the CNS. |
| Length: | 128 |
| Pfam Domains: | 36-92 Homeobox domain |
| Sequence: (in bold interface residues) | 1 GSDIDDPSSETDSKKGGSRNGDGKSGGGGGGGSKPRRARTAFTYEQLVSLENKFKTTRYL 60 61 SVCERLNLALSLSLTETQVKIWFQNRRTKWKKQNPGMDVNSPTIPPPGGGSFGPGAYASG 120 121 LLYSHAVP |
| Interface Residues: | 36, 37, 38, 39, 41, 77, 78, 80, 81, 84, 85, 88, 89, 92 |
| 3D-footprint Homologues: | 1fjl_B, 6a8r_A, 2h1k_B, 1puf_A, 1ig7_A, 3cmy_A, 5zfz_A, 3d1n_M, 3lnq_A, 2lkx_A, 1mnm_C, 1jgg_B, 6m3d_C, 1nk2_P, 1zq3_P, 2ld5_A, 3l1p_A, 3a01_E, 7q3o_C, 1b72_A, 5jlw_D, 6es3_K, 4xrs_G, 2hdd_A, 3rkq_B, 2r5y_A, 5flv_I, 2hos_A, 4cyc_A, 5hod_A, 1le8_A, 7xrc_C, 1e3o_C, 2xsd_C, 1au7_A, 1o4x_A, 4qtr_D, 1du0_A, 1puf_B, 8g87_X, 5zjt_E, 1k61_B, 7psx_B |
| Binding Motifs: | UP00510A_1 myacTgrrcTAATTAscsbrdr |
| Binding Sites: | GGTAATTA ACCAATTA ACTAATTA AGTAATTA ATAATTAG ATTAATTA CAATTAAG CCTAATTA CTAATTAA CTAATTAC CTAATTAG CTTAATTA GATAATTA GCAATTAA GCTAATTA GTAATTAA GTAATTAC GTTAATTA TAATTAAA TTAATTAA |
| Publications: | Busser BW, Shokri L, Jaeger SA, Gisselbrecht SS, Singhania A, Berger MF, Zhou B, Bulyk ML, Michelson AM. Molecular mechanism underlying the regulatory specificity of a Drosophila homeodomain protein that specifies myoblast identity. Development 139:1164-74 (2012). [Pubmed] |
| Related annotations: | PaperBLAST |
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