DNA Binding Motif

						

			
Accessions: UP00169A_1 (UniPROBE 20160601)

			
Names: LIM homeobox transcription factor 1 beta, LIM-homeobox protein 1.2, LIM/homeobox protein LMX1B, LMX-1.2, LMX1.1, LMX1.2, Lmx1b
Organisms: Mus musculus
Libraries: UniPROBE 20160601 1
1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed]
Length: 17
Consensus: rrwwwTTAATTAAtwyb
Weblogo: 
PSSM: P0      A      C      G      T
01   0.34   0.22   0.31   0.14      r
02   0.25   0.13   0.39   0.23      r
03   0.32   0.09   0.15   0.44      w
04   0.37   0.05   0.09   0.49      w
05   0.36   0.09   0.06   0.49      w
06   0.02   0.16   0.02   0.80      T
07   0.02   0.02      0   0.96      T
08   0.97   0.01      0   0.02      A
09   0.98      0   0.01   0.02      A
10   0.02   0.01      0   0.98      T
11   0.02      0   0.01   0.97      T
12   0.96      0   0.02   0.02      A
13   0.80   0.02   0.16   0.02      A
14   0.24   0.12   0.12   0.53      t
15   0.28   0.10   0.19   0.43      w
16   0.25   0.26   0.14   0.36      y
17   0.14   0.25   0.35   0.26      b
Binding TFs: UP00169A (Homeobox domain, Homeobox KN domain)
Binding Sites: AAATTAAT
AATAATTA
AATTAAAA
AATTAAAT
AATTAATA
AATTAATT
ACTAATTA
ATAATTAA
ATAATTAG
ATTAATAA
ATTAATTA
CTAATTAA
CTAATTAG
CTTAATTA
GCTAATTA
GTAATTAA
GTTAATTA
TAATTAAA
TAATTAGA
TTATTAAA
			
Publications: Berger M.F, Badis G, Gehrke A.R, Talukder S, Philippakis A.A, Peña-Castillo L, Alleyne T.M, Mnaimneh S, Botvinnik O.B, Chan E.T, Khalid F, Zhang W, Newburger D, Jaeger S.A, Morris Q.D, Bulyk M.L, Hughes T.R. Variation in homeodomain DNA binding revealed by high-resolution analysis of sequence preferences. Cell 133:1266-76 (2008). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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