Transcription Factor

Accessions: UP00121A (UniPROBE 20160601)
Names: AI385591, AI874987, homeo box D10, Homeobox protein Hox-D10, Hox-4.5, Hox-5.3, Hoxd-10, Hoxd10
Organisms: Mus musculus
Libraries: UniPROBE 20160601 1
1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed]
Uniprot: P28359
Description: homeo box D10
Length: 90
Pfam Domains: 17-73 Homeobox domain
Sequence:
(in bold interface residues)
1 IKSDTPTSNWLTAKSGRKKRCPYTKHQTLELEKEFLFNMYLTRERRLEISKSVNLTDRQV 60
61 KIWFQNRRMKLKKMSRENRIRELTANLTFS
Interface Residues: 17, 18, 19, 20, 58, 59, 61, 62, 65, 66, 69, 70, 73
3D-footprint Homologues: 1ig7_A, 6a8r_A, 2h1k_B, 6m3d_C, 1puf_A, 3cmy_A, 5zfz_A, 1fjl_B, 3d1n_M, 1zq3_P, 2lkx_A, 1nk2_P, 2ld5_A, 6es3_K, 7q3o_C, 5hod_A, 3a01_E, 1jgg_B, 5jlw_D, 3lnq_A, 4xrs_G, 2hdd_A, 7psx_B, 1au7_A, 3rkq_B, 2r5y_A, 1puf_B, 5flv_I, 2hos_A, 1b72_A, 5zjt_E, 4cyc_A, 2xsd_C, 7xrc_C, 1e3o_C, 1le8_A, 6fqq_E, 3l1p_A, 1o4x_A, 1du0_A, 4qtr_D, 8g87_X, 6fqp_B
Binding Motifs: UP00121A_1 mrkgyAATAAAAtwwww
Binding Sites: TAATAAAA
AATAAAAT
AATAATTA
AATTAATA
ATAATAAA
ATAATTAA
ATAATTAC
ATTAATGA
ATTAATTA
ATTTAATG
CATAAAAA
GCAATAAA
GTAATAAA
GTCATAAA
GTCATTAA
GTCGTAAA
TAATTAAA
TCATAAAA
TCATTAAA
TCGTAAAA
Publications: Berger M.F, Badis G, Gehrke A.R, Talukder S, Philippakis A.A, Peña-Castillo L, Alleyne T.M, Mnaimneh S, Botvinnik O.B, Chan E.T, Khalid F, Zhang W, Newburger D, Jaeger S.A, Morris Q.D, Bulyk M.L, Hughes T.R. Variation in homeodomain DNA binding revealed by high-resolution analysis of sequence preferences. Cell 133:1266-76 (2008). [Pubmed]
Related annotations: PaperBLAST

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.