Transcription Factor

Accessions: UP00260A (UniPROBE 20160601)
Names: homeo box C6, Homeobox protein Hox-C6, Hox-3.3, Hox-6.1, Hoxc-6, Hoxc6
Organisms: Mus musculus
Libraries: UniPROBE 20160601 1
1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed]
Uniprot: P10629
Description: homeo box C6
Length: 93
Pfam Domains: 17-73 Homeobox domain
Sequence:
(in bold interface residues)
1 MQRMNSHSGVGYGADRRRGRQIYSRYQTLELEKEFHFNRYLTRRRRIEIANALCLTERQI 60
61 KIWFQNRRMKWKKESNLTSTLSGGGGGATADSL
Interface Residues: 16, 17, 18, 19, 20, 21, 58, 59, 61, 62, 65, 66, 69, 70, 73
3D-footprint Homologues: 3a01_E, 1fjl_B, 5zfz_A, 1ig7_A, 4j19_B, 2h1k_B, 1puf_A, 6a8r_A, 3cmy_A, 3d1n_M, 1nk2_P, 1zq3_P, 6m3d_C, 1jgg_B, 3lnq_A, 2lkx_A, 2ld5_A, 6es3_K, 4xrs_G, 2hos_A, 4cyc_A, 5flv_I, 5zjt_E, 7psx_B, 5hod_A, 2hdd_A, 7q3o_C, 5jlw_D, 3rkq_B, 2r5y_A, 1puf_B, 7xrc_C, 2xsd_C, 1e3o_C, 1le8_A, 1b72_A, 3l1p_A, 1o4x_A, 1du0_A, 4qtr_D
Binding Motifs: UP00260A_1 yrarkTAATTAmtwamw
Binding Sites: GGTAATTA
AATAATTA
AATTAATA
ACTAATTA
AGTAATTA
ATAATTAC
ATAATTAT
ATTAATGA
ATTAATTA
ATTAATTG
CATAATTA
CTAATTAG
CTTAATTA
GATAATTA
GCAATTAA
GTAATTAA
GTAATTAC
GTCATTAA
GTTAATTA
TAATTAAA
Publications: Berger M.F, Badis G, Gehrke A.R, Talukder S, Philippakis A.A, Peña-Castillo L, Alleyne T.M, Mnaimneh S, Botvinnik O.B, Chan E.T, Khalid F, Zhang W, Newburger D, Jaeger S.A, Morris Q.D, Bulyk M.L, Hughes T.R. Variation in homeodomain DNA binding revealed by high-resolution analysis of sequence preferences. Cell 133:1266-76 (2008). [Pubmed]
Related annotations: PaperBLAST

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.