DNA Binding Motif

						

			
Accessions: UP00158A_1 (UniPROBE 20160601)

			
Names: dw, dwarf, GHF-1, Growth hormone factor 1, Hmp1, Pit-1, Pit1, pituitary specific transcription factor 1, Pituitary-specific positive transcription factor 1, Pou1f1
Organisms: Mus musculus
Libraries: UniPROBE 20160601 1
1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed]
Length: 17
Consensus: rrwtAATTAATTAwgtc
Weblogo: 
PSSM: P0      A      C      G      T
01   0.30   0.14   0.33   0.24      r
02   0.39   0.24   0.26   0.12      r
03   0.27   0.19   0.20   0.34      w
04   0.09   0.05   0.21   0.65      t
05   0.80   0.10   0.02   0.08      A
06   0.89   0.04   0.02   0.05      A
07   0.06   0.01   0.01   0.92      T
08   0.03   0.02   0.02   0.93      T
09   0.93   0.02   0.02   0.03      A
10   0.92   0.01   0.01   0.06      A
11   0.05   0.02   0.04   0.89      T
12   0.08   0.02   0.10   0.80      T
13   0.79   0.09   0.02   0.10      A
14   0.43   0.11   0.21   0.25      w
15   0.24   0.19   0.33   0.24      g
16   0.22   0.14   0.20   0.44      t
17   0.15   0.48   0.18   0.18      c
Binding TFs: UP00158A (Homeobox domain, Pou domain - N-terminal to homeobox domain)
Binding Sites: ATGCAAAT
AATAATTA
ACTAATTA
ACTCATTA
ATAATGAG
ATAATTAA
ATAATTAG
ATTAATTA
ATTATGCA
ATTATGCG
CATAATTA
CCTCATTA
CTAATTAA
CTAATTAG
CTCATTAA
CTTAATTA
GCTAATTA
GTTAATTA
TAATTAAA
TTAATTAA
			
Publications: Berger M.F, Badis G, Gehrke A.R, Talukder S, Philippakis A.A, Peña-Castillo L, Alleyne T.M, Mnaimneh S, Botvinnik O.B, Chan E.T, Khalid F, Zhang W, Newburger D, Jaeger S.A, Morris Q.D, Bulyk M.L, Hughes T.R. Variation in homeodomain DNA binding revealed by high-resolution analysis of sequence preferences. Cell 133:1266-76 (2008). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.