Transcription Factor
| Accessions: | UP00158A (UniPROBE 20160601) |
| Names: | dw, dwarf, GHF-1, Growth hormone factor 1, Hmp1, Pit-1, Pit1, pituitary specific transcription factor 1, Pituitary-specific positive transcription factor 1, Pou1f1 |
| Organisms: | Mus musculus |
| Libraries: | UniPROBE 20160601 1 1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed] |
| Uniprot: | Q00286 |
| Description: | pituitary specific transcription factor 1 |
| Length: | 183 |
| Pfam Domains: | 17-90 Pou domain - N-terminal to homeobox domain 107-163 Homeobox domain |
| Sequence: (in bold interface residues) | 1 QELRRKSKLVEEPIDMDSPEIRELEQFANEFKVRRIKLGYTQTNVGEALAAVHGSEFSQT 60 61 TICRFENLQLSFKNACKLKAILSKWLEEAEQVGALYNEKVGANERKRKRRTTISVAAKDA 120 121 LERHFGEHSKPSSQEIMRMAEELNLEKEVVRVWFCNRRQREKRVKTSLNQSLFSISKEHL 180 181 ECR |
| Interface Residues: | 42, 58, 59, 60, 61, 63, 64, 66, 67, 70, 74, 107, 108, 109, 110, 148, 149, 151, 152, 155, 156, 159, 160, 163 |
| 3D-footprint Homologues: | 3d1n_M, 3l1p_A, 7u0g_M, 8g87_X, 1o4x_A, 2xsd_C, 1e3o_C, 1au7_A, 7xrc_C, 2d5v_B, 1ig7_A, 5zfz_A, 6fqp_B, 1fjl_B, 6a8r_A, 3cmy_A, 1zq3_P, 2lkx_A, 1nk2_P, 2ld5_A, 1b72_A, 5jlw_D, 3rkq_B, 2r5y_A, 4xrs_G, 2hos_A, 1jgg_B, 5flv_I, 5zjt_E, 2h1k_B, 5hod_A, 3lnq_A, 1puf_B, 2hdd_A, 7psx_B, 7q3o_C, 1le8_A, 6es3_K, 1du0_A, 4cyc_A, 1puf_A, 4qtr_D, 3a01_E, 4xrm_B, 6m3d_C |
| Binding Motifs: | UP00158A_1 rrwtAATTAATTAwgtc |
| Binding Sites: | ATGCAAAT AATAATTA ACTAATTA ACTCATTA ATAATGAG ATAATTAA ATAATTAG ATTAATTA ATTATGCA ATTATGCG CATAATTA CCTCATTA CTAATTAA CTAATTAG CTCATTAA CTTAATTA GCTAATTA GTTAATTA TAATTAAA TTAATTAA |
| Publications: | Berger M.F, Badis G, Gehrke A.R, Talukder S, Philippakis A.A, Peña-Castillo L, Alleyne T.M, Mnaimneh S, Botvinnik O.B, Chan E.T, Khalid F, Zhang W, Newburger D, Jaeger S.A, Morris Q.D, Bulyk M.L, Hughes T.R. Variation in homeodomain DNA binding revealed by high-resolution analysis of sequence preferences. Cell 133:1266-76 (2008). [Pubmed] |
| Related annotations: | PaperBLAST |
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.