Transcription Factor
| Accessions: | UP00177A (UniPROBE 20160601) |
| Names: | homeo box D12, Homeobox protein Hox-D12, Hox-4.7, Hox-5.6, Hoxd-12, Hoxd12 |
| Organisms: | Mus musculus |
| Libraries: | UniPROBE 20160601 1 1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed] |
| Uniprot: | P23812 |
| Description: | homeo box D12 |
| Length: | 84 |
| Pfam Domains: | 17-73 Homeobox domain |
| Sequence: (in bold interface residues) | 1 SPKPGLPWGGAAPGRARKKRKPYTKQQIAELENEFLVNEFINRQKRKELSNRLNLSDQQV 60 61 KIWFQNRRMKKKRVVQREQALALY |
| Interface Residues: | 17, 18, 19, 20, 21, 58, 59, 61, 62, 65, 66, 69, 70, 72, 73 |
| 3D-footprint Homologues: | 1puf_A, 3cmy_A, 6a8r_A, 3d1n_M, 1fjl_B, 1ig7_A, 5zfz_A, 2h1k_B, 1nk2_P, 1zq3_P, 6m3d_C, 2lkx_A, 7q3o_C, 6es3_K, 2ld5_A, 1jgg_B, 5zjt_E, 2hdd_A, 7psx_B, 5hod_A, 3rkq_B, 2r5y_A, 1puf_B, 2hos_A, 5jlw_D, 4cyc_A, 1b72_A, 4xrs_G, 4j19_B, 3a01_E, 3lnq_A, 3l1p_A, 1e3o_C, 1au7_A, 2xsd_C, 1le8_A, 7xrc_C, 8g87_X, 4qtr_D, 1mnm_C, 1k61_B, 4xrm_B, 1o4x_A, 1le8_B, 1du0_A, 5flv_I |
| Binding Motifs: | UP00177A_1 ywavGTCGTAAAatywt |
| Binding Sites: | TAATAAAA AATAAAAC AATAAAAT ATAATAAA ATCGTAAA ATTTACGA ATTTATTA CAATAAAA CTAATAAA CTCGTAAA GCAATAAA GTAATAAA GTAATTAA GTCATAAA GTCGTTAA GTTTACGA TAATTAAA TCATAAAA TCGTAAAA TCGTTAAA |
| Publications: | Berger M.F, Badis G, Gehrke A.R, Talukder S, Philippakis A.A, Peña-Castillo L, Alleyne T.M, Mnaimneh S, Botvinnik O.B, Chan E.T, Khalid F, Zhang W, Newburger D, Jaeger S.A, Morris Q.D, Bulyk M.L, Hughes T.R. Variation in homeodomain DNA binding revealed by high-resolution analysis of sequence preferences. Cell 133:1266-76 (2008). [Pubmed] |
| Related annotations: | PaperBLAST |
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.