Transcription Factor

Accessions: UP00262A (UniPROBE 20160601)
Names: Homeobox protein Lim-1, Lhx1, LIM homeobox protein 1, LIM/homeobox protein Lhx1, Lim1
Organisms: Mus musculus
Libraries: UniPROBE 20160601 1
1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed]
Uniprot: P63006
Description: LIM homeobox protein 1
Length: 93
Pfam Domains: 17-73 Homeobox domain
39-68 Homeobox KN domain
Sequence:
(in bold interface residues)
1 EGGSNENDDQNLGAKRRGPRTTIKAKQLETLKAAFAATPKPTRHIREQLAQETGLNMRVI 60
61 QVWFQNRRSKERRMKQLSALGARRHAFFRSPRR
Interface Residues: 16, 17, 19, 20, 58, 59, 61, 62, 65, 66, 69, 70, 72, 73
3D-footprint Homologues: 2ld5_A, 4j19_B, 3a01_E, 1ig7_A, 2lkx_A, 1puf_A, 5zjt_E, 3cmy_A, 1fjl_B, 3d1n_M, 5jlw_D, 1b72_A, 4cyc_A, 4xrs_G, 3l1p_A, 5zfz_A, 2h1k_B, 1jgg_B, 6m3d_C, 3lnq_A, 2hdd_A, 1au7_A, 5hod_A, 3rkq_B, 2r5y_A, 6a8r_A, 2hos_A, 2xsd_C, 7xrc_C, 1e3o_C, 1le8_A, 7q3o_C, 1zq3_P, 6es3_K, 1o4x_A, 1du0_A, 5flv_I, 8g87_X, 4qtr_D, 7psx_B, 1puf_B, 4xrm_B, 1nk2_P
Binding Motifs: UP00262A_1 mgwaTTAATTAAwwahk
Binding Sites: AATAATTA
AATTAATA
AATTAATT
ACTAATTA
AGTAATTA
ATAATTAA
ATAATTAG
ATTAATTA
ATTAATTG
CCTAATTA
CTAATTAA
CTAATTAG
CTTAATTA
GATAATTA
GCTAATTA
GTAATTAA
GTTAATTA
TAATTAAA
TAATTACA
TAATTATA
Publications: Berger M.F, Badis G, Gehrke A.R, Talukder S, Philippakis A.A, Peña-Castillo L, Alleyne T.M, Mnaimneh S, Botvinnik O.B, Chan E.T, Khalid F, Zhang W, Newburger D, Jaeger S.A, Morris Q.D, Bulyk M.L, Hughes T.R. Variation in homeodomain DNA binding revealed by high-resolution analysis of sequence preferences. Cell 133:1266-76 (2008). [Pubmed]
Related annotations: PaperBLAST

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.