Transcription Factor

Accessions: UP00164A (UniPROBE 20160601)
Names: AV118143, homeo box A7, Homeobox protein Hox-A7, Hox-1.1, Hoxa-7, Hoxa7, M6, M6-12
Organisms: Mus musculus
Libraries: UniPROBE 20160601 1
1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed]
Description: homeo box A7
Length: 93
Pfam Domains: 17-73 Homeobox domain
Sequence:
(in bold interface residues)
1 ASFRIYPWMRSSGPDRKRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQI 60
61 KIWFQNRRMKWKKEHKDESQAPTAAPEDAVPSV
Interface Residues: 15, 17, 18, 19, 20, 21, 58, 59, 61, 62, 65, 66, 69, 70, 73
3D-footprint Homologues: 1puf_A, 6a8r_A, 2h1k_B, 3cmy_A, 5zfz_A, 1fjl_B, 1ig7_A, 1jgg_B, 3lnq_A, 2lkx_A, 6m3d_C, 3d1n_M, 1zq3_P, 1nk2_P, 5hod_A, 3a01_E, 7q3o_C, 5jlw_D, 6es3_K, 4xrs_G, 2hdd_A, 3rkq_B, 2r5y_A, 1puf_B, 5flv_I, 2hos_A, 1b72_A, 5zjt_E, 4cyc_A, 2ld5_A, 1e3o_C, 1le8_A, 7xrc_C, 2xsd_C, 3l1p_A, 1o4x_A, 1du0_A, 4qtr_D, 8g87_X, 7psx_B
Binding Motifs: UP00164A_1 sgmrtTAATTAatwagc
UP00164A_2 kkmkTAATTAmkggmm
Binding Sites: GGTAATTA
AATAATTA
AATTAATA
AGTAATTA
ATAATTAA
ATAATTAC
ATTAATAG
ATTAATGA
ATTAATTA
ATTAATTG
CTAATTAA
CTTAATTA
GCAATTAA
GCTAATTA
GTAATTAA
GTAATTAC
GTCATTAA
GTTAATTA
TAATTAAA
TAATTATA
Publications: Berger M.F, Badis G, Gehrke A.R, Talukder S, Philippakis A.A, Peña-Castillo L, Alleyne T.M, Mnaimneh S, Botvinnik O.B, Chan E.T, Khalid F, Zhang W, Newburger D, Jaeger S.A, Morris Q.D, Bulyk M.L, Hughes T.R. Variation in homeodomain DNA binding revealed by high-resolution analysis of sequence preferences. Cell 133:1266-76 (2008). [Pubmed]
Related annotations: PaperBLAST

Disclaimer and license

These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.