Transcription Factor
| Accessions: | UP00266A (UniPROBE 20160601) |
| Names: | A230024N07Rik, AA755424, AI385634, AI843499, Homeobox protein K-2, Homeobox protein mHox, Paired mesoderm homeobox protein 1, paired related homeobox 1, Paired-related homeobox protein 1, Pmx, Pmx1, Prrx1, PRX-1, Prx1 |
| Organisms: | Mus musculus |
| Libraries: | UniPROBE 20160601 1 1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed] |
| Uniprot: | P63013 |
| Description: | paired related homeobox 1 |
| Length: | 93 |
| Pfam Domains: | 17-73 Homeobox domain |
| Sequence: (in bold interface residues) | 1 QDNDQLNSEEKKKRKQRRNRTTFNSSQLQALERVFERTHYPDAFVREDLARRVNLTEARV 60 61 QVWFQNRRAKFRRNERAMLANKNASLLKSYSGD |
| Interface Residues: | 17, 18, 19, 20, 58, 59, 61, 62, 65, 66, 69, 70, 73, 77 |
| 3D-footprint Homologues: | 3cmy_A, 1ig7_A, 3d1n_M, 5zfz_A, 2h1k_B, 1puf_A, 1fjl_B, 6a8r_A, 1nk2_P, 1zq3_P, 1jgg_B, 6m3d_C, 3lnq_A, 2lkx_A, 2ld5_A, 2hdd_A, 7q3o_C, 5jlw_D, 3rkq_B, 2r5y_A, 6es3_K, 4xrs_G, 2hos_A, 4cyc_A, 1au7_A, 5flv_I, 3l1p_A, 5zjt_E, 4j19_B, 3a01_E, 2h8r_B, 7psx_B, 1b72_A, 5hod_A, 1puf_B, 1ic8_B, 7xrc_C, 1e3o_C, 2xsd_C, 1le8_A, 1du0_A, 1o4x_A, 8g87_X, 4qtr_D |
| Binding Motifs: | UP00266A_1 vkaayTAATTAryTast |
| Binding Sites: | AATTAATT ACCAATTA ACTAATTA AGTAATTA ATAATTAA ATAATTAG ATTAATTA CCAATTAA CCAATTAG CCTAATTA CTAATTAA CTAATTAC CTAATTAG CTTAATTA GCTAATTA GTAATTAA GTTAATTA TAATTAAA TAATTAGA TTAATTAA |
| Publications: | Berger M.F, Badis G, Gehrke A.R, Talukder S, Philippakis A.A, Peña-Castillo L, Alleyne T.M, Mnaimneh S, Botvinnik O.B, Chan E.T, Khalid F, Zhang W, Newburger D, Jaeger S.A, Morris Q.D, Bulyk M.L, Hughes T.R. Variation in homeodomain DNA binding revealed by high-resolution analysis of sequence preferences. Cell 133:1266-76 (2008). [Pubmed] |
| Related annotations: | PaperBLAST |
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.