Transcription Factor

Accessions: UP00144A (UniPROBE 20160601)
Names: homeo box B4, Homeobox protein Hox-B4, Hox-2.6, Hoxb-4, Hoxb4
Organisms: Mus musculus
Libraries: UniPROBE 20160601 1
1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed]
Uniprot: P10284
Description: homeo box B4
Length: 93
Pfam Domains: 17-73 Homeobox domain
Sequence:
(in bold interface residues)
1 KVHVSTVNPNYAGGEPKRSRTAYTRQQVLELEKEFHYNRYLTRRRRVEIAHALCLSERQI 60
61 KIWFQNRRMKWKKDHKLPNTKIRSGGTAGAAGG
Interface Residues: 17, 18, 19, 20, 58, 59, 61, 62, 65, 66, 69, 70, 73
3D-footprint Homologues: 5zfz_A, 3d1n_M, 1fjl_B, 6a8r_A, 2h1k_B, 1puf_A, 1ig7_A, 3cmy_A, 1jgg_B, 6m3d_C, 1nk2_P, 1zq3_P, 3lnq_A, 2lkx_A, 2ld5_A, 3rkq_B, 2r5y_A, 5flv_I, 2hos_A, 5zjt_E, 4cyc_A, 7psx_B, 5hod_A, 3l1p_A, 3a01_E, 7q3o_C, 1b72_A, 5jlw_D, 6es3_K, 4xrs_G, 2hdd_A, 1e3o_C, 2xsd_C, 1le8_A, 7xrc_C, 1du0_A, 1puf_B, 8g87_X, 1k61_B, 1o4x_A, 4qtr_D, 1mnm_C
Binding Motifs: UP00144A_1 cgmrTTAATTAAtwahy
Binding Sites: GGTAATTA
AATAATTA
ACTAATTA
AGTAATTA
ATAATTAA
ATAATTAC
ATCATTAA
ATTAATGA
ATTAATTA
CATTAATG
CTAATTAA
CTAATTAG
CTTAATTA
GATAATTA
GCTAATTA
GTAATTAA
GTCATTAA
GTTAATGA
GTTAATTA
TAATTAAA
Publications: Berger M.F, Badis G, Gehrke A.R, Talukder S, Philippakis A.A, Peña-Castillo L, Alleyne T.M, Mnaimneh S, Botvinnik O.B, Chan E.T, Khalid F, Zhang W, Newburger D, Jaeger S.A, Morris Q.D, Bulyk M.L, Hughes T.R. Variation in homeodomain DNA binding revealed by high-resolution analysis of sequence preferences. Cell 133:1266-76 (2008). [Pubmed]
Related annotations: PaperBLAST

Disclaimer and license

These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.