DNA Binding Motif

Accessions: UP00178A_1 (UniPROBE 20160601)
Names: Nobox, OG2 homeobox gene, Og2x
Organisms: Mus musculus
Libraries: UniPROBE 20160601 1
1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed]
Length: 17
Consensus: cgsryyAATTrrkways
Weblogo:
PSSM: P0 A C G T
01 0.17 0.50 0.20 0.13 c
02 0.13 0.18 0.54 0.16 g
03 0.23 0.28 0.25 0.23 s
04 0.31 0.23 0.36 0.10 r
05 0.02 0.58 0.03 0.38 y
06 0.02 0.33 0 0.65 y
07 0.92 0.01 0.07 0.01 A
08 0.96 0 0.01 0.03 A
09 0.03 0.01 0 0.96 T
10 0.01 0.07 0.01 0.92 T
11 0.65 0 0.33 0.02 r
12 0.38 0.03 0.58 0.02 r
13 0.14 0.16 0.39 0.30 k
14 0.30 0.19 0.16 0.35 w
15 0.44 0.16 0.16 0.24 a
16 0.23 0.29 0.17 0.31 y
17 0.15 0.41 0.25 0.19 s
Binding TFs: UP00178A (Homeobox domain)
Binding Sites: ACCAATTA
ACTAATTA
ATAATTGG
ATCAATTA
ATTAATTA
ATTAATTG
CAATTAAC
CAATTAAG
CCAATTAA
CCAATTAG
CTAATTAA
CTAATTAG
CTAATTGA
CTTAATTA
GCAATTAA
GCCAATTA
GCTAATTA
GTTAATTA
TAATTAAA
TCAATTAA
Publications: Berger M.F, Badis G, Gehrke A.R, Talukder S, Philippakis A.A, Peña-Castillo L, Alleyne T.M, Mnaimneh S, Botvinnik O.B, Chan E.T, Khalid F, Zhang W, Newburger D, Jaeger S.A, Morris Q.D, Bulyk M.L, Hughes T.R. Variation in homeodomain DNA binding revealed by high-resolution analysis of sequence preferences. Cell 133:1266-76 (2008). [Pubmed]

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