DNA Binding Motif

						

			
Accessions: UP00106A_1 (UniPROBE 20160601)

			
Names: Vax2, Ventral anterior homeobox 2, ventral anterior homeobox containing gene 2, Ventral retina homeodomain protein, Vex
Organisms: Mus musculus
Libraries: UniPROBE 20160601 1
1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed]
Length: 16
Consensus: kwvcryTAATTArkrc
Weblogo: 
PSSM: P0      A      C      G      T
01   0.16   0.24   0.31   0.30      k
02   0.32   0.16   0.19   0.33      w
03   0.26   0.26   0.27   0.21      v
04   0.17   0.43   0.21   0.18      c
05   0.53   0.13   0.26   0.08      r
06   0.06   0.56   0.12   0.25      y
07   0.01   0.11      0   0.88      T
08   0.88   0.11      0      0      A
09   0.98      0      0   0.01      A
10   0.01      0      0   0.99      T
11      0      0   0.02   0.98      T
12   0.93      0   0.03   0.03      A
13   0.50   0.19   0.25   0.06      r
14   0.08   0.23   0.41   0.28      k
15   0.34   0.21   0.31   0.13      r
16   0.17   0.58   0.17   0.09      c
Binding TFs: UP00106A (Homeobox domain)
Binding Sites: GGTAATTA
AATAATTA
ACTAATTA
AGTAATTA
ATAATTAC
ATAATTAG
ATTAATTA
CATAATTA
CCTAATTA
CTAATTAA
CTAATTAG
CTCATTAA
CTTAATTA
GATAATTA
GCTAATTA
GTAATTAA
GTAATTAC
GTTAATTA
TAATTAAA
TTAATTAA
			
Publications: Berger M.F, Badis G, Gehrke A.R, Talukder S, Philippakis A.A, Peña-Castillo L, Alleyne T.M, Mnaimneh S, Botvinnik O.B, Chan E.T, Khalid F, Zhang W, Newburger D, Jaeger S.A, Morris Q.D, Bulyk M.L, Hughes T.R. Variation in homeodomain DNA binding revealed by high-resolution analysis of sequence preferences. Cell 133:1266-76 (2008). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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