Transcription Factor

Accessions: UP00238A (UniPROBE 20160601)
Names: 9130417I07Rik, locus 3 (Drosophila), NK6 transcription factor related, Nkx6-3, Nkx6.3
Organisms: Mus musculus
Libraries: UniPROBE 20160601 1
1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed]
Uniprot: Q9D2W8
Description: NK6 transcription factor related, locus 3 (Drosophila)
Length: 93
Pfam Domains: 17-73 Homeobox domain
Sequence:
(in bold interface residues)
1 HTDKAPDPLSDTIHKKKHTRPTFTGHQIFALEKTFEQTKYLAGPERARLAYSLGMTESQV 60
61 KVWFQNRRTKWRKKSALEPSSSTPRAPGGASGD
Interface Residues: 17, 18, 20, 58, 59, 61, 62, 65, 66, 69, 70, 73
3D-footprint Homologues: 3cmy_A, 3d1n_M, 5zfz_A, 2h1k_B, 1puf_A, 1fjl_B, 6a8r_A, 1nk2_P, 1zq3_P, 2lkx_A, 2hdd_A, 7q3o_C, 1b72_A, 5jlw_D, 3rkq_B, 2r5y_A, 1ig7_A, 6es3_K, 4xrs_G, 2hos_A, 4cyc_A, 1jgg_B, 6m3d_C, 5flv_I, 3l1p_A, 2ld5_A, 5zjt_E, 3a01_E, 7psx_B, 5hod_A, 3lnq_A, 1le8_A, 7xrc_C, 2xsd_C, 1e3o_C, 1au7_A, 4xrm_B, 1puf_B, 1du0_A, 1o4x_A, 8g87_X, 4qtr_D, 1k61_B
Binding Motifs: UP00238A_1 gawwwTTAATKAmtkyk
Binding Sites: GGTAATTA
AATAATTA
AATTAATA
AATTAATG
AATTAATT
AGTAATTA
ATAATTAA
ATAATTAC
ATAATTAT
ATTAATGA
ATTAATTG
CTAATTAA
CTCATTAA
GATAATTA
GCAATTAA
GTAATTAA
GTCATTAA
TAATTAAA
TCATTAAA
TTAATTAA
Publications: Berger M.F, Badis G, Gehrke A.R, Talukder S, Philippakis A.A, Peña-Castillo L, Alleyne T.M, Mnaimneh S, Botvinnik O.B, Chan E.T, Khalid F, Zhang W, Newburger D, Jaeger S.A, Morris Q.D, Bulyk M.L, Hughes T.R. Variation in homeodomain DNA binding revealed by high-resolution analysis of sequence preferences. Cell 133:1266-76 (2008). [Pubmed]
Related annotations: PaperBLAST

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.