Transcription Factor
| Accessions: | UP00063A (UniPROBE 20160601), UP00391A (UniPROBE 20160601) |
| Names: | homeo box A3, Homeobox protein Hox-A3, Hox-1.5, Hoxa-3, Hoxa3, Mo-10 |
| Organisms: | Mus musculus |
| Libraries: | UniPROBE 20160601 1 1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed] |
| Uniprot: | P02831 |
| Description: | homeo box A3: Mus musculus homeo box A3 (Hoxa3) |
| Length: | 93 |
| Pfam Domains: | 17-73 Homeobox domain |
| Sequence: (in bold interface residues) | 1 GESCAGDKSPPGQASSKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQI 60 61 KIWFQNRRMKYKKDQKGKGMLTSSGGQSPSRSP |
| Interface Residues: | 8, 17, 18, 19, 20, 58, 59, 61, 62, 65, 66, 69, 70, 73 |
| 3D-footprint Homologues: | 3a01_E, 1fjl_B, 5zfz_A, 1ig7_A, 2h1k_B, 1puf_A, 6a8r_A, 3cmy_A, 3d1n_M, 1nk2_P, 1zq3_P, 6m3d_C, 1jgg_B, 3lnq_A, 2lkx_A, 2ld5_A, 3rkq_B, 2r5y_A, 6es3_K, 4xrs_G, 2hos_A, 1b72_A, 4cyc_A, 5flv_I, 5zjt_E, 4j19_B, 7psx_B, 5hod_A, 2hdd_A, 7q3o_C, 5jlw_D, 7xrc_C, 2xsd_C, 1e3o_C, 1le8_A, 1au7_A, 1puf_B, 3l1p_A, 1o4x_A, 1du0_A, 4qtr_D |
| Binding Motifs: | UP00063A_1 tkgagbTAATTAry UP00391A_1 tygmrbTAATTAry UP00063A_2 aarawCbATTArsr |
| Binding Sites: | GGTAATTA AATAATTA ACTAATTA AGTAATTA ATAATTAC ATTAATTA CTAATTAA CTAATTAC CTAATTAG CTCATTAA CTTAATTA GCTAATTA GTAATTAA GTAATTAC GTCATTAA GTTAATGA GTTAATTA TAATTAAA TAATTACA TTAATTAA |
| Publications: | Badis G, Berger M.F, Philippakis A.A, Talukder S, Gehrke A.R, Jaeger S.A, Chan E.T, Metzler G, Vedenko A, Chen X, Kuznetsov H, Wang C.F, Coburn D, Newburger D.E, Morris Q, Hughes T.R, Bulyk M.L. Diversity and complexity in DNA recognition by transcription factors. Science (New York, N.Y.) 324:1720-3 (2009). [Pubmed] Berger M.F, Badis G, Gehrke A.R, Talukder S, Philippakis A.A, Peña-Castillo L, Alleyne T.M, Mnaimneh S, Botvinnik O.B, Chan E.T, Khalid F, Zhang W, Newburger D, Jaeger S.A, Morris Q.D, Bulyk M.L, Hughes T.R. Variation in homeodomain DNA binding revealed by high-resolution analysis of sequence preferences. Cell 133:1266-76 (2008). [Pubmed] |
| Related annotations: | PaperBLAST |
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.