Transcription Factor
| Accessions: | UP00127A (UniPROBE 20160601), P31316 (JASPAR 2024) |
| Names: | genomic screened homeo box 2, Gsh-2, Gsh2, Homeobox protein GSH-2, Genetic-screened homeobox 2, GS homeobox 2, GSX2_MOUSE |
| Organisms: | Mus musculus |
| Libraries: | UniPROBE 20160601 1, JASPAR 2024 2 1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed] 2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Description: | genomic screened homeo box 2 |
| Length: | 305 |
| Pfam Domains: | 204-260 Homeobox domain |
| Sequence: (in bold interface residues) | 1 MSRSFYVDSLIIKDSSRPAPSLPESHPGPDFFIPLGMPSPLVMSVSGPGCPSRKSGAFCV 60 61 CPLCVTSHLHSSRPPAGAGGGATGTAGAAVAGGGVAGGTGALPLLKSQFSPAPGDAQFCP 120 121 RVSHAHHHHHPPQHHHHHHQPQQPGSAAAAAAAAAAAAAAAAALGHPQHHAPVCAATTYN 180 181 MSDPRRFHCLSMGGSDTSQVPNGKRMRTAFTSTQLLELEREFSSNMYLSRLRRIEIATYL 240 241 NLSEKQVKIWFQNRRVKHKKEGKGASRNNHTSCKCVGSQAHYARSEDEDSLSPASANEDK 300 301 EISPL |
| Interface Residues: | 180, 181, 182, 185, 186, 192, 196, 204, 205, 206, 207, 208, 245, 246, 248, 249, 252, 253, 256, 257, 260 |
| 3D-footprint Homologues: | 1e3o_C, 1puf_A, 1ig7_A, 3cmy_A, 5zfz_A, 1fjl_B, 6a8r_A, 2h1k_B, 3lnq_A, 2lkx_A, 1jgg_B, 6m3d_C, 3d1n_M, 1zq3_P, 6es3_K, 1nk2_P, 2ld5_A, 7q3o_C, 1b72_A, 5jlw_D, 4xrs_G, 2hdd_A, 3rkq_B, 2r5y_A, 1puf_B, 5flv_I, 2hos_A, 5zjt_E, 4cyc_A, 7psx_B, 5hod_A, 3a01_E, 7xrc_C, 2xsd_C, 1au7_A, 1le8_A, 1mnm_C, 1du0_A, 8g87_X, 1k61_B, 3l1p_A, 1o4x_A, 4qtr_D |
| Binding Motifs: | UP00127A_1 asryTAATTAgyysAk PH0036.1 asryTAATTAgyysAk |
| Binding Sites: | GGTAATTA AATTAATT ACTAATTA AGTAATTA ATAATTAA ATAATTAG ATTAATGA ATTAATTA CCTAATTA CTAATTAA CTAATTAC CTAATTAG CTTAATTA GATAATTA GCTAATTA GTAATTAA GTAATTAC GTTAATTA TAATTAAA TTAATTAA |
| Publications: | Berger M.F, Badis G, Gehrke A.R, Talukder S, Philippakis A.A, Peña-Castillo L, Alleyne T.M, Mnaimneh S, Botvinnik O.B, Chan E.T, Khalid F, Zhang W, Newburger D, Jaeger S.A, Morris Q.D, Bulyk M.L, Hughes T.R. Variation in homeodomain DNA binding revealed by high-resolution analysis of sequence preferences. Cell 133:1266-76 (2008). [Pubmed] |
| Related annotations: | PaperBLAST |
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.