Transcription Factor

Accessions: UP00237A (UniPROBE 20160601)
Names: Homeobox protein orthopediaÂ, orthopedia homolog (Drosophila), Otp
Organisms: Mus musculus
Libraries: UniPROBE 20160601 1
1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed]
Uniprot: O09113
Description: orthopedia homolog (Drosophila)
Length: 93
Pfam Domains: 17-73 Homeobox domain
Sequence:
(in bold interface residues)
1 GPNPSQAGQQQGQQKQKRHRTRFTPAQLNELERSFAKTHYPDIFMREELALRIGLTESRV 60
61 QVWFQNRRAKWKKRKKTTNVFRAPGTLLPTPGL
Interface Residues: 17, 18, 19, 20, 22, 58, 59, 61, 62, 65, 66, 69, 70, 72, 73
3D-footprint Homologues: 2h1k_B, 1puf_A, 6a8r_A, 3cmy_A, 1fjl_B, 3d1n_M, 5zfz_A, 4j19_B, 1jgg_B, 3lnq_A, 2lkx_A, 1nk2_P, 1zq3_P, 6m3d_C, 6es3_K, 7q3o_C, 2ld5_A, 3a01_E, 5hod_A, 2hdd_A, 1au7_A, 3rkq_B, 2r5y_A, 4xrs_G, 2hos_A, 1b72_A, 4cyc_A, 1ig7_A, 5flv_I, 3l1p_A, 5jlw_D, 1e3o_C, 1le8_A, 2xsd_C, 7xrc_C, 8g87_X, 4qtr_D, 7psx_B, 1puf_B, 1o4x_A, 1du0_A, 5zjt_E, 6x1j_A
Binding Motifs: UP00237A_1 cryarTTAATTAAykkg
Binding Sites: AATAATTA
AATTAATT
AATTAGTG
ACTAATTA
AGTAATTA
ATAATTAA
ATAATTAG
ATTAATTA
CATAATTA
CCTAATTA
CTAATTAA
CTAATTAC
CTAATTAG
CTTAATTA
GCTAATTA
GTAATTAA
GTTAATTA
TAATTAAA
TAATTAGA
TAATTATA
Publications: Berger M.F, Badis G, Gehrke A.R, Talukder S, Philippakis A.A, Peña-Castillo L, Alleyne T.M, Mnaimneh S, Botvinnik O.B, Chan E.T, Khalid F, Zhang W, Newburger D, Jaeger S.A, Morris Q.D, Bulyk M.L, Hughes T.R. Variation in homeodomain DNA binding revealed by high-resolution analysis of sequence preferences. Cell 133:1266-76 (2008). [Pubmed]
Related annotations: PaperBLAST

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.