Transcription Factor
| Accessions: | UP00235A (UniPROBE 20160601), P31313 (JASPAR 2024) |
| Names: | homeo box C11, Homeobox protein Hox-C11, Hox-3.7, Hoxc-11, Hoxc11, Homeobox protein Hox-3.7, HXC11_MOUSE |
| Organisms: | Mus musculus |
| Libraries: | UniPROBE 20160601 1, JASPAR 2024 2 1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed] 2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Uniprot: | P31313 |
| Description: | homeo box C11 |
| Length: | 304 |
| Pfam Domains: | 42-178 Protein of unknown function (DUF3528) 233-289 Homeobox domain |
| Sequence: (in bold interface residues) | 1 MFNSVNLGNFCSPSRKERGADFGERGSCTSNLYLPSCTYYVPEFSTVSSFLPQAPSRQIS 60 61 YPYSAQVPPVREVSYGLEPSGKWHHRNSYSSCYAAADELMHRECLPPSTVTEILMKNEGS 120 121 YGGHHHPSAPHAAPAGFYSSVNKNSVLPQAFDRFFDNAYCGGGDAPAEPPCSGKGEAKGE 180 181 PEAPPASGLASRAEAGAEAEAEEENTNPSSSGSSHSATKEPAKGAAPNAPRTRKKRCPYS 240 241 KFQIRELEREFFFNVYINKEKRLQLSRMLNLTDRQVKIWFQNRRMKEKKLSRDRLQYFSG 300 301 NPLL |
| Interface Residues: | 233, 234, 235, 236, 274, 275, 277, 278, 281, 282, 285, 286, 289 |
| 3D-footprint Homologues: | 5zfz_A, 1ig7_A, 2h1k_B, 1puf_A, 3cmy_A, 6a8r_A, 1fjl_B, 1zq3_P, 2lkx_A, 3lnq_A, 1nk2_P, 2ld5_A, 7q3o_C, 1b72_A, 3rkq_B, 5flv_I, 3a01_E, 5zjt_E, 4cyc_A, 1jgg_B, 6m3d_C, 2hdd_A, 2r5y_A, 1puf_B, 7psx_B, 5jlw_D, 2hos_A, 6es3_K, 4xrs_G, 1le8_A, 7xrc_C, 1e3o_C, 1au7_A, 2xsd_C, 1o4x_A, 6fqq_E, 1le8_B, 1du0_A, 5hod_A, 1mnm_C, 4qtr_D, 1k61_B |
| Binding Motifs: | UP00235A_1 yaarGTCGTAAAayrk PH0067.1 ywrgGTCGTAAAwwywc |
| Binding Sites: | TAATAAAA AATAAAAT ATCGTAAA ATCGTTAA ATTTACGA ATTTTATG CAATAAAA CATAAAAC CCATAAAA CTCGTAAA GTAATAAA GTCATAAA GTCATTAA GTCGTTAA GTTTACGA TAATTAAA TCATAAAA TCATTAAA TCGTAAAA TCGTTAAA |
| Publications: | Berger M.F, Badis G, Gehrke A.R, Talukder S, Philippakis A.A, Peña-Castillo L, Alleyne T.M, Mnaimneh S, Botvinnik O.B, Chan E.T, Khalid F, Zhang W, Newburger D, Jaeger S.A, Morris Q.D, Bulyk M.L, Hughes T.R. Variation in homeodomain DNA binding revealed by high-resolution analysis of sequence preferences. Cell 133:1266-76 (2008). [Pubmed] |
| Related annotations: | PaperBLAST |
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.