DNA Binding Motif

						

			
Accessions: UP00118A_1 (UniPROBE 20160601)

			
Names: Brain-specific homeobox/POU domain protein 3C, Brn-3.1, Brn-3c, Brn3.1, Brn3c, class 4, ddl, dreidel, POU domain, Pou4f3, transcription factor 3
Organisms: Mus musculus
Libraries: UniPROBE 20160601 1
1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed]
Length: 16
Consensus: wrtwATTAATkArkyc
Weblogo: 
PSSM: P0      A      C      G      T
01   0.38   0.20   0.16   0.26      w
02   0.29   0.23   0.35   0.13      r
03   0.18   0.07   0.19   0.55      t
04   0.25   0.22   0.01   0.52      w
05   0.93   0.01   0.01   0.05      A
06   0.01   0.02      0   0.97      T
07   0.02      0      0   0.98      T
08   0.97      0      0   0.03      A
09   0.99      0      0   0.01      A
10   0.01   0.01      0   0.98      T
11   0.06   0.01   0.56   0.37      k
12   0.94   0.03   0.01   0.02      A
13   0.31   0.12   0.35   0.22      r
14   0.08   0.11   0.50   0.32      k
15   0.22   0.27   0.06   0.45      y
16   0.19   0.55   0.06   0.21      c
Binding TFs: UP00118A (Homeobox domain, Pou domain - N-terminal to homeobox domain)
Binding Sites: AAATTAAT
AATTAATA
AATTAATG
AATTAATT
ATAATTAA
ATATTAAT
ATTAATAA
ATTAATTA
CATTAATA
CATTAATG
CCTCATTA
CTAATTAA
CTAATTAG
CTCATTAA
CTTAATTA
GTTAATTA
TAATTAAA
TATTAATA
TCATTAAA
TTAATTAA
			
Publications: Berger M.F, Badis G, Gehrke A.R, Talukder S, Philippakis A.A, Peña-Castillo L, Alleyne T.M, Mnaimneh S, Botvinnik O.B, Chan E.T, Khalid F, Zhang W, Newburger D, Jaeger S.A, Morris Q.D, Bulyk M.L, Hughes T.R. Variation in homeodomain DNA binding revealed by high-resolution analysis of sequence preferences. Cell 133:1266-76 (2008). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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