Transcription Factor
| Accessions: | UP00154A (UniPROBE 20160601) |
| Names: | AV237891, DII C, distal-less homeobox 3, Dlx-3, Dlx3, Homeobox protein DLX-3 |
| Organisms: | Mus musculus |
| Libraries: | UniPROBE 20160601 1 1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed] |
| Uniprot: | Q64205 |
| Description: | distal-less homeobox 3 |
| Length: | 93 |
| Pfam Domains: | 17-73 Homeobox domain |
| Sequence: (in bold interface residues) | 1 EPEAEVRMVNGKPKKVRKPRTIYSSYQLAALQRRFQKAQYLALPERAELAAQLGLTQTQV 60 61 KIWFQNRRSKFKKLYKNGEVPLEHSPNNSDSMA |
| Interface Residues: | 17, 18, 19, 20, 58, 59, 61, 62, 65, 66, 69, 70, 73 |
| 3D-footprint Homologues: | 3cmy_A, 1mnm_C, 6a8r_A, 3d1n_M, 1fjl_B, 5zfz_A, 2h1k_B, 1puf_A, 1ig7_A, 5zjt_E, 1nk2_P, 1zq3_P, 6m3d_C, 2lkx_A, 7q3o_C, 6es3_K, 2ld5_A, 2hdd_A, 7psx_B, 5hod_A, 3rkq_B, 2r5y_A, 1jgg_B, 2hos_A, 5jlw_D, 4cyc_A, 1au7_A, 4xrs_G, 4j19_B, 3a01_E, 1b72_A, 5flv_I, 3lnq_A, 1e3o_C, 2xsd_C, 7xrc_C, 1le8_A, 1du0_A, 1puf_B, 4xrm_B, 1k61_B, 3l1p_A, 1o4x_A, 8g87_X, 4qtr_D |
| Binding Motifs: | UP00154A_1 kmrmdaTAATTAcmswm |
| Binding Sites: | GGTAATTA AATAATTA ACTAATTA AGTAATTA ATAATTAG ATAATTAT ATAATTGC ATTAATTA CATAATTA CTAATTAA CTAATTAG GATAATTA GCAATTAA GCTAATTA GTAATTAA GTAATTAC TAATTAAA TAATTACA TAATTATA TTAATTAA |
| Publications: | Berger M.F, Badis G, Gehrke A.R, Talukder S, Philippakis A.A, Peña-Castillo L, Alleyne T.M, Mnaimneh S, Botvinnik O.B, Chan E.T, Khalid F, Zhang W, Newburger D, Jaeger S.A, Morris Q.D, Bulyk M.L, Hughes T.R. Variation in homeodomain DNA binding revealed by high-resolution analysis of sequence preferences. Cell 133:1266-76 (2008). [Pubmed] |
| Related annotations: | PaperBLAST |
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