Transcription Factor

Accessions: UP00140A (UniPROBE 20160601)
Names: homeo box D1, Homeobox protein Hox-D1, Hox-4.9, Hoxd-1, Hoxd1
Organisms: Mus musculus
Libraries: UniPROBE 20160601 1
1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed]
Uniprot: Q01822
Description: homeo box D1
Length: 93
Pfam Domains: 20-73 Homeobox domain
Sequence:
(in bold interface residues)
1 APKKSKLSEYGATSPPSAIRTNFSTKQLTELEKEFHFNKYLTRARRIEIANCLQLNDTQV 60
61 KIWFQNRRMKQKKREREGLLATAASVASIKLPR
Interface Residues: 13, 18, 19, 20, 58, 59, 61, 62, 65, 66, 69, 70, 73
3D-footprint Homologues: 3a01_E, 1zq3_P, 7q3o_C, 1b72_A, 5zfz_A, 4cyc_A, 1ig7_A, 6m3d_C, 5flv_I, 2ld5_A, 5zjt_E, 2h1k_B, 1jgg_B, 7psx_B, 5hod_A, 3lnq_A, 2lkx_A, 1puf_A, 6a8r_A, 3cmy_A, 2hdd_A, 1au7_A, 5jlw_D, 3rkq_B, 2r5y_A, 1puf_B, 1fjl_B, 6es3_K, 4xrs_G, 3d1n_M, 2hos_A, 1nk2_P, 2xsd_C, 1e3o_C, 1le8_A, 7xrc_C, 3l1p_A, 1o4x_A, 8g87_X, 1du0_A, 4qtr_D, 4j19_B
Binding Motifs: UP00140A_2 ywarGTCGTAAAawyht
UP00140A_1 mrkgyAATAAAAtwwww
UP00140A_5 wraryTAATTArytgkw
UP00140A_3 ywavGTCGTAAAatywt
UP00140A_4 mwwyyAATAAAAhymh
Binding Sites: TAATAAAA
AATAAAAT
AATAATTA
AATTAATA
ATAATAAA
ATAATTAA
ATAATTAC
ATTAATGA
ATTAATTA
ATTTAATG
CATAAAAA
GCAATAAA
GTAATAAA
GTCATAAA
GTCATTAA
GTCGTAAA
TAATTAAA
TCATAAAA
TCATTAAA
TCGTAAAA
Publications: Berger M.F, Badis G, Gehrke A.R, Talukder S, Philippakis A.A, Peña-Castillo L, Alleyne T.M, Mnaimneh S, Botvinnik O.B, Chan E.T, Khalid F, Zhang W, Newburger D, Jaeger S.A, Morris Q.D, Bulyk M.L, Hughes T.R. Variation in homeodomain DNA binding revealed by high-resolution analysis of sequence preferences. Cell 133:1266-76 (2008). [Pubmed]
Related annotations: PaperBLAST

Disclaimer and license

These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.