DNA Binding Site
| Accessions: | GCAATAAA (UniPROBE 20160601), MA0465.3.5 (JASPAR 2024), MA0650.4.15 (JASPAR 2024), MA0650.4.4 (JASPAR 2024) |
| Organisms: | Mus musculus, Drosophila melanogaster, Homo sapiens |
| Libraries: | UniPROBE 20160601 1, JASPAR 2024 2 1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed] 2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Length: | 8 |
| Sequence: | GCAATAAA |
| Type: | Heterodimer |
| Binding TFs: | Q62424 (Homeobox domain, Hox protein A13 N terminal) UP00117A (Homeobox domain) UP00121A (Homeobox domain) UP00133A (Homeobox domain) UP00134A (Homeobox domain) UP00135A (Homeobox domain) UP00140A (Homeobox domain) UP00168A (Homeobox domain) UP00173A (Homeobox domain, Homeobox KN domain) UP00177A (Homeobox domain) UP00180A (Homeobox domain) UP00183A (Homeobox domain) UP00197A (Homeobox domain) UP00207A (Homeobox domain) UP00213A (Homeobox domain) UP00217A (Homeobox domain) UP00240A (Homeobox domain) UP00245A (Homeobox domain) UP00246A (Homeobox domain) UP00264A (Homeobox domain) Q99626 (Homeobox domain, Caudal like protein activation region) UP00503A (Homeobox domain) UP00597A (Homeobox domain) UP00597B (Homeobox domain) UP00597D (Homeobox domain) UP00597G (Homeobox domain) UP00597H (Homeobox domain) Q62424 Q99626 |
| Binding Motifs: | UP00117A_1 / UP00140A_2 ywarGTCGTAAAawyht UP00121A_1 / UP00140A_1 mrkgyAATAAAAtwwww UP00133A_1 drvgGymATAAAayky UP00134A_1 mrmCyAATAAAAwwys UP00135A_1 ywrgGTCGTAAAwwywc UP00140A_5 wraryTAATTArytgkw UP00168A_1 taadTAATTAATrgctw UP00173A_1 wwwkCTCrTAAAawtw UP00140A_3 / UP00177A_1 ywavGTCGTAAAatywt UP00140A_4 / UP00180A_1 mwwyyAATAAAAhymh UP00183A_1 / UP00264A_3 wwwbCTCGTAAAawtt UP00197A_1 rkagGTMATWAAyydk UP00207A_1 rrrgymATWAAAwycr UP00213A_1 rcggycATwAAAwtadw UP00217A_1 / UP00264A_1 dmgGyMATWAAAtkmw UP00240A_1 wrmGGYmATWAAatkw UP00245A_1 twarGTCRTAAAaysk UP00246A_1 / UP00264A_2 waarGTCRTAAAayrk UP00264A_4 ctrarcTAATTAmyky UP00503A_1 ggrarrgGymATWAAattyhba UP00597A_1 ykrsmthymATWAAawvcmgth UP00597B_1 tksmrytyaATAAAAwwcdmtt UP00597D_1 tkswwyyyaATAAAAwwcmmtt UP00597G_2 wrkmrayYAATAAAAwwcwmtt UP00597H_1 kksmrcyyAATAAAAwwmavtt UP00597H_2 cwdwwwkCTCrTAAAawtdgmd MA0465.3 GCAATAAA MA0650.4 CCAATAAA |
| Publications: | Berger M.F, Badis G, Gehrke A.R, Talukder S, Philippakis A.A, Peña-Castillo L, Alleyne T.M, Mnaimneh S, Botvinnik O.B, Chan E.T, Khalid F, Zhang W, Newburger D, Jaeger S.A, Morris Q.D, Bulyk M.L, Hughes T.R. Variation in homeodomain DNA binding revealed by high-resolution analysis of sequence preferences. Cell 133:1266-76 (2008). [Pubmed] Verzi M.P, Hatzis P, Sulahian R, Philips J, Schuijers J, Shin H, Freed E, Lynch J.P, Dang D.T, Brown M, Clevers H, Liu X.S, Shivdasani R.A. TCF4 and CDX2, major transcription factors for intestinal function, converge on the same cis-regulatory regions. Proceedings of the National Academy of Sciences of the United States of America 107:15157-62 (2010). [Pubmed] Knosp W. M., Saneyoshi C., Shou S., Bachinger H. P., Stadler H. S. Elucidation, quantitative refinement, and in vivo utilization of the HOXA13 DNA binding site.. J. Biol. Chem. 282:6843-6853 (2007). [Pubmed] |
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