DNA Binding Motif

Accessions: UP00245A_1 (UniPROBE 20160601)
Names: AI506621, homeo box C10, Homeobox protein Hox-C10, Hox-3.6, Hoxc-10, Hoxc10
Organisms: Mus musculus
Libraries: UniPROBE 20160601 1
1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed]
Length: 16
Consensus: twarGTCRTAAAaysk
Weblogo:
PSSM: P0 A C G T
01 0.24 0.24 0.13 0.39 t
02 0.39 0.12 0.24 0.25 w
03 0.43 0.16 0.18 0.23 a
04 0.34 0.14 0.29 0.23 r
05 0.08 0.06 0.86 0 G
06 0 0.04 0 0.96 T
07 0.02 0.98 0 0 C
08 0.30 0 0.70 0 R
09 0 0 0 0.99 T
10 0.85 0 0 0.14 A
11 0.99 0 0 0.01 A
12 0.98 0.01 0 0.01 A
13 0.50 0.13 0.15 0.23 a
14 0.22 0.33 0.15 0.30 y
15 0.21 0.26 0.29 0.25 s
16 0.14 0.15 0.30 0.41 k
Binding TFs: UP00245A (Homeobox domain)
Binding Sites: TAATAAAA
GGTAATTA
ATAATTAC
ATCGTAAA
ATTTTATG
CAATAAAA
CCATAAAA
CCCATAAA
CTCGTAAA
GCAATAAA
GGTCGTAA
GGTCGTTA
GTAATAAA
GTAATTAC
GTCATAAA
GTCATTAA
GTCGTTAA
GTTTACGA
TCATAAAA
TCGTAAAA
Publications: Berger M.F, Badis G, Gehrke A.R, Talukder S, Philippakis A.A, Peña-Castillo L, Alleyne T.M, Mnaimneh S, Botvinnik O.B, Chan E.T, Khalid F, Zhang W, Newburger D, Jaeger S.A, Morris Q.D, Bulyk M.L, Hughes T.R. Variation in homeodomain DNA binding revealed by high-resolution analysis of sequence preferences. Cell 133:1266-76 (2008). [Pubmed]

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