Transcription Factor

Accessions: UP00117A (UniPROBE 20160601)
Names: homeo box D11, Homeobox protein Hox-D11, Hox-4.6, Hox-5.4, Hox-5.5, Hoxd-11, Hoxd11
Organisms: Mus musculus
Libraries: UniPROBE 20160601 1
1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed]
Uniprot: P23813
Description: homeo box D11
Length: 88
Pfam Domains: 17-73 Homeobox domain
Sequence:
(in bold interface residues)
1 EAGAEKSGGTVAPQRSRKKRCPYTKYQIRELEREFFFNVYINKEKRLQLSRMLNLTDRQV 60
61 KIWFQNRRMKEKKLNRDRLQYFTGNPLF
Interface Residues: 15, 17, 18, 19, 20, 23, 58, 59, 61, 62, 65, 66, 69, 70, 73
3D-footprint Homologues: 6fqp_B, 1ig7_A, 6a8r_A, 2h1k_B, 1puf_A, 3cmy_A, 5zfz_A, 3d1n_M, 1fjl_B, 2lkx_A, 1nk2_P, 1zq3_P, 2ld5_A, 6es3_K, 7q3o_C, 3a01_E, 6m3d_C, 5jlw_D, 3lnq_A, 1jgg_B, 4xrs_G, 2hdd_A, 7psx_B, 3rkq_B, 2r5y_A, 1puf_B, 5flv_I, 2hos_A, 5zjt_E, 4cyc_A, 1b72_A, 5hod_A, 7xrc_C, 1e3o_C, 1au7_A, 2xsd_C, 1le8_A, 1o4x_A, 4qtr_D, 1le8_B, 1du0_A, 8g87_X, 1mnm_C, 1k61_B, 6fqq_E, 3l1p_A
Binding Motifs: UP00117A_1 ywarGTCGTAAAawyht
Binding Sites: TAATAAAA
AATAAAAT
ATAAAAAG
ATCGTAAA
ATTTACGA
CAATAAAA
CATAAAAA
CCATAAAA
CTCGTAAA
GCAATAAA
GGTCGTAA
GTAATAAA
GTCATAAA
GTCATTAA
GTCGTTAA
GTTTACGA
TCATAAAA
TCATTAAA
TCGTAAAA
ATTAACGA
Publications: Berger M.F, Badis G, Gehrke A.R, Talukder S, Philippakis A.A, Peña-Castillo L, Alleyne T.M, Mnaimneh S, Botvinnik O.B, Chan E.T, Khalid F, Zhang W, Newburger D, Jaeger S.A, Morris Q.D, Bulyk M.L, Hughes T.R. Variation in homeodomain DNA binding revealed by high-resolution analysis of sequence preferences. Cell 133:1266-76 (2008). [Pubmed]
Related annotations: PaperBLAST

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.