Transcription Factor
| Accessions: | UP00133A (UniPROBE 20160601) |
| Names: | caudal type homeo box 2, Caudal-type homeobox protein 2, Cdx-2, Cdx2, Homeobox protein CDX-2 |
| Organisms: | Mus musculus |
| Libraries: | UniPROBE 20160601 1 1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed] |
| Uniprot: | P43241 |
| Description: | caudal type homeo box 2 |
| Length: | 93 |
| Pfam Domains: | 18-73 Homeobox domain |
| Sequence: (in bold interface residues) | 1 KPAQQSLGSQVKTRTKDKYRVVYTDHQRLELEKEFHFSRYITIRRKSELAATLGLSERQV 60 61 KIWFQNRRAKERKIKKKQQQQQQQQQQQPPQPP |
| Interface Residues: | 12, 14, 17, 18, 19, 20, 58, 59, 61, 62, 65, 66, 69, 70, 71, 73 |
| 3D-footprint Homologues: | 2lkx_A, 1puf_A, 3lnq_A, 1jgg_B, 1nk2_P, 6es3_K, 7q3o_C, 2ld5_A, 7psx_B, 5jlw_D, 4xrs_G, 3cmy_A, 2hdd_A, 5zfz_A, 3rkq_B, 2r5y_A, 6m3d_C, 5flv_I, 2hos_A, 1fjl_B, 4cyc_A, 1ig7_A, 6a8r_A, 3a01_E, 2h1k_B, 1e3o_C, 1au7_A, 7xrc_C, 2xsd_C, 1le8_A, 1le8_B, 1du0_A, 1mnm_C, 1puf_B, 1k61_B, 3d1n_M, 5zjt_E, 1zq3_P, 6wig_A, 1b72_A, 5hod_A, 3l1p_A, 1o4x_A, 8g87_X, 4qtr_D |
| Binding Motifs: | UP00133A_1 drvgGymATAAAayky |
| Binding Sites: | TAATAAAA AATAAAAT AATAAACC ACCATAAA ATAATAAA ATCATAAA ATTTATGA ATTTATGG ATTTATTA CAATAAAA CAATAAAC CCATAAAA GCAATAAA GCAATTAA GCCATAAA GTCATAAA GTCGTAAA GTTTATTA TCAATAAA TCATAAAA |
| Publications: | Berger M.F, Badis G, Gehrke A.R, Talukder S, Philippakis A.A, Peña-Castillo L, Alleyne T.M, Mnaimneh S, Botvinnik O.B, Chan E.T, Khalid F, Zhang W, Newburger D, Jaeger S.A, Morris Q.D, Bulyk M.L, Hughes T.R. Variation in homeodomain DNA binding revealed by high-resolution analysis of sequence preferences. Cell 133:1266-76 (2008). [Pubmed] |
| Related annotations: | PaperBLAST |
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.