DNA Binding Site
| Accessions: | GCAATTAA (UniPROBE 20160601), MA0465.3.7 (JASPAR 2024), MA0885.3.8 (JASPAR 2024), MA1476.3.13 (JASPAR 2024), MA1476.3.15 (JASPAR 2024), MA1476.3.19 (JASPAR 2024), MA1476.3.5 (JASPAR 2024) |
| Organisms: | Mus musculus, Saccharomyces cerevisiae, Drosophila melanogaster, Homo sapiens |
| Libraries: | UniPROBE 20160601 1, JASPAR 2024 2 1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed] 2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Length: | 8 |
| Sequence: | GCAATTAA |
| Type: | Heterodimer |
| Binding TFs: | P70396 (Homeobox domain, Homeobox protein distal-less-like N terminal ) P40764 (Homeobox domain, Homeobox protein distal-less-like N terminal ) UP00078A (ARID/BRIGHT DNA binding domain) UP00110A (Homeobox domain) UP00126A (Homeobox domain) UP00133A (Homeobox domain) UP00138A (Homeobox domain) UP00139A (Homeobox domain) UP00145A (Homeobox domain) UP00151A (Homeobox domain) UP00154A (Homeobox domain) UP00155A (Homeobox domain) UP00166A (Homeobox domain) UP00168A (Homeobox domain) UP00171A (Homeobox domain) UP00178A (Homeobox domain) UP00181A (Homeobox domain) UP00182A (Homeobox domain) UP00189A (Homeobox domain) UP00197A (Homeobox domain) UP00202A (Homeobox domain) UP00204A (Homeobox domain) UP00206A (Homeobox domain) UP00207A (Homeobox domain) UP00213A (Homeobox domain) UP00214A (Homeobox domain) UP00217A (Homeobox domain) UP00220A (Homeobox domain) UP00230A (Homeobox domain) UP00234A (Homeobox domain) UP00238A (Homeobox domain) UP00240A (Homeobox domain) UP00242A (Homeobox domain) UP00244A (Homeobox domain) UP00252A (Homeobox domain) UP00259A (Homeobox domain) UP00260A (Homeobox domain) UP00264A (Homeobox domain) UP00274A (Homeobox domain) Q99626 (Homeobox domain, Caudal like protein activation region) UP00157A (Homeobox domain) UP00164A (Homeobox domain) UP00507A (Homeobox domain) UP00510A (Homeobox domain) UP00512A (Homeobox domain) UP00598B (Homeobox domain) UP00603A (Homeobox domain) UP00603B (Homeobox domain) UP00603C (Homeobox domain) P40764 P70396 Q99626 |
| Binding Motifs: | UP00259A_1 wwtksgTAATTACsdy UP00078A_1 sgktTTAATTAAwmtwy UP00110A_1 bcrcdaTAATTAcmswc UP00126A_1 vrdrYAATTRbhymag UP00133A_1 drvgGymATAAAayky UP00138A_1 vmrgyAATTrsytsAd UP00139A_1 dtbcryYAATTRrtrcw UP00145A_1 aamAAcCAATTAAswh UP00151A_1 taakYAATTRrtkrtr UP00154A_1 kmrmdaTAATTAcmswm UP00155A_1 acaAgCAATTAAwgvrT UP00157A_1 asaAgCAATTAAwrrat UP00164A_1 sgmrtTAATTAatwagc UP00166A_1 aamAAcCAATTArkwc UP00168A_1 taadTAATTAATrgctw UP00171A_1 mamAAcyAATTAAktw UP00178A_1 cgsryyAATTrrkways UP00181A_1 marsyAATTrsygaaw UP00182A_1 amgkTAATTACcymak UP00264A_3 wwwbCTCGTAAAawtt UP00189A_1 amgkTAATTAscwmar UP00197A_1 rkagGTMATWAAyydk UP00202A_1 btgarrTAATTAay UP00204A_1 wdsmaCYAATTRGtgbw UP00206A_1 stakTAATTAmtkshr UP00207A_1 rrrgymATWAAAwycr UP00213A_1 rcggycATwAAAwtadw UP00214A_1 amgkTAATTAschmat UP00217A_1 / UP00264A_1 dmgGyMATWAAAtkmw UP00220A_1 wgmrcyAATTrgyGsgr UP00230A_1 ssrgyAATTrsykmts UP00234A_1 krmwayTAATTAatwm UP00238A_1 gawwwTTAATKAmtkyk UP00240A_1 wrmGGYmATWAAatkw UP00242A_1 twkrrgTAATTAhykt UP00244A_1 kwatyAATTAATaayww UP00264A_2 waarGTCRTAAAayrk UP00252A_1 cgmrtTAATTAatwayt UP00260A_1 yrarkTAATTAmtwamw UP00264A_4 ctrarcTAATTAmyky UP00274A_1 ttsmmaYTAATTARwwwmks UP00078A_2 hmmvrtATcrdrtyk UP00164A_2 kkmkTAATTAmkggmm UP00507A_1 tarcrsCrCyAATTAgygywyy UP00510A_1 myacTgrrcTAATTAscsbrdr UP00512A_1 aawraarGGTAATTAmydkwkw UP00598B_1 ykyrscmYTAATTAAkmwsckg UP00598B_2 gkcmscryTAATTArkvhkssb UP00603A_1 mtwyaaaAAcCAATTAacwmray UP00603A_2 bwyraaaacYAATTAaywhwmby UP00603B_1 wtwtrtgyAATTAwttaaktysw UP00603C_1 awwsydrACYAATTAdsgcmdy MA0465.3 GCAATAAA MA0885.3 GCAATTAG MA1476.3 GCAATTAg |
| Publications: | Badis G, Berger M.F, Philippakis A.A, Talukder S, Gehrke A.R, Jaeger S.A, Chan E.T, Metzler G, Vedenko A, Chen X, Kuznetsov H, Wang C.F, Coburn D, Newburger D.E, Morris Q, Hughes T.R, Bulyk M.L. Diversity and complexity in DNA recognition by transcription factors. Science (New York, N.Y.) 324:1720-3 (2009). [Pubmed] Verzi M.P, Hatzis P, Sulahian R, Philips J, Schuijers J, Shin H, Freed E, Lynch J.P, Dang D.T, Brown M, Clevers H, Liu X.S, Shivdasani R.A. TCF4 and CDX2, major transcription factors for intestinal function, converge on the same cis-regulatory regions. Proceedings of the National Academy of Sciences of the United States of America 107:15157-62 (2010). [Pubmed] Berger M.F, Badis G, Gehrke A.R, Talukder S, Philippakis A.A, Peña-Castillo L, Alleyne T.M, Mnaimneh S, Botvinnik O.B, Chan E.T, Khalid F, Zhang W, Newburger D, Jaeger S.A, Morris Q.D, Bulyk M.L, Hughes T.R. Variation in homeodomain DNA binding revealed by high-resolution analysis of sequence preferences. Cell 133:1266-76 (2008). [Pubmed] |
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