DNA Binding Motif

Accessions: UP00242A_1 (UniPROBE 20160601)
Names: D130011F21Rik, homeo box C8, Homeobox protein Hox-C8, Hox-3.1, Hoxc-8, Hoxc8, M31
Organisms: Mus musculus
Libraries: UniPROBE 20160601 1
1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed]
Length: 16
Consensus: twkrrgTAATTAhykt
Weblogo:
PSSM: P0 A C G T
01 0.21 0.22 0.24 0.32 t
02 0.28 0.19 0.09 0.44 w
03 0.24 0.10 0.41 0.25 k
04 0.32 0.10 0.36 0.23 r
05 0.29 0.17 0.37 0.17 r
06 0.13 0.07 0.56 0.24 g
07 0.01 0.08 0 0.91 T
08 0.91 0.05 0 0.04 A
09 0.97 0.01 0 0.01 A
10 0.01 0 0.01 0.97 T
11 0.04 0 0.05 0.91 T
12 0.91 0 0.08 0.01 A
13 0.35 0.33 0.04 0.28 h
14 0.17 0.37 0.17 0.29 y
15 0.21 0.10 0.42 0.28 k
16 0.09 0.16 0.17 0.59 t
Binding TFs: UP00242A (Homeobox domain)
Binding Sites: GGTAATTA
AATAATTA
AATTAATA
AATTAATT
ACTAATTA
AGTAATTA
ATAATTAA
ATAATTAC
ATTAATTA
ATTAATTG
CATTAATG
CTAATTAG
CTTAATTA
GATAATTA
GCAATTAA
GTAATTAA
GTAATTAC
GTCATTAA
GTTAATTA
TTAATTAA
Publications: Berger M.F, Badis G, Gehrke A.R, Talukder S, Philippakis A.A, Peña-Castillo L, Alleyne T.M, Mnaimneh S, Botvinnik O.B, Chan E.T, Khalid F, Zhang W, Newburger D, Jaeger S.A, Morris Q.D, Bulyk M.L, Hughes T.R. Variation in homeodomain DNA binding revealed by high-resolution analysis of sequence preferences. Cell 133:1266-76 (2008). [Pubmed]

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