DNA Binding Motif

Accessions: UP00507A_1 (UniPROBE 20160601)
Names: 153515_at, 99B, CG1897, Dmel\CG1897, l(3)FA30, ltt, Msh, msh-1, msh1, Msx, Muscle segmentation homeobox, Protein drop, Protein msh
Organisms: Drosophila melanogaster
Libraries: UniPROBE 20160601 1
1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed]
Length: 22
Consensus: tarcrsCrCyAATTAgygywyy
Weblogo:
PSSM: P0 A C G T
01 0.17 0.24 0.15 0.45 t
02 0.43 0.19 0.22 0.16 a
03 0.32 0.23 0.32 0.13 r
04 0.21 0.37 0.25 0.18 c
05 0.29 0.24 0.28 0.19 r
06 0.19 0.33 0.36 0.12 s
07 0.10 0.70 0.14 0.06 C
08 0.61 0.09 0.29 0.01 r
09 0.02 0.73 0.14 0.11 C
10 0 0.45 0 0.55 y
11 0.98 0.02 0 0 A
12 0.99 0 0 0 A
13 0.01 0 0 0.99 T
14 0 0 0 0.99 T
15 0.83 0 0.16 0 A
16 0.17 0.13 0.62 0.08 g
17 0.06 0.50 0.06 0.38 y
18 0.14 0.14 0.47 0.24 g
19 0.09 0.31 0.19 0.42 y
20 0.41 0.06 0.03 0.50 w
21 0.20 0.41 0.11 0.27 y
22 0.22 0.27 0.20 0.32 y
Binding TFs: UP00507A (Homeobox domain)
Binding Sites: GGTAATTA
ACCAATTA
ACTAATTA
AGCAATTA
AGTAATTA
ATAATTAC
ATAATTAG
ATAATTGG
ATTAATTA
CAATTAAA
CCAATTAA
CCAATTAG
CCTAATTA
CTAATTAA
CTAATTAC
CTAATTAG
GATAATTA
GCAATTAA
GCTAATTA
GTAATTAA
Publications: Busser BW, Shokri L, Jaeger SA, Gisselbrecht SS, Singhania A, Berger MF, Zhou B, Bulyk ML, Michelson AM. Molecular mechanism underlying the regulatory specificity of a Drosophila homeodomain protein that specifies myoblast identity. Development 139:1164-74 (2012). [Pubmed]

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