Transcription Factor
| Accessions: | P40764 (JASPAR 2024) |
| Names: | DLX2_MOUSE, Homeobox protein DLX-2, Homeobox protein TES-1 |
| Organisms: | Mus musculus |
| Libraries: | JASPAR 2024 1 1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Length: | 332 |
| Pfam Domains: | 54-134 Homeobox protein distal-less-like N terminal 156-212 Homeobox domain |
| Sequence: (in bold interface residues) | 1 MTGVFDSLVADMHSTQITASSTYHQHQQPPSGAGAGPGGNSNSSSSNSSLHKPQESPTLP 60 61 VSTATDSSYYTNQQHPAGGGGGGASPYAHMGSYQYHASGLNNVSYSAKSSYDLGYTAAYT 120 121 SYAPYGTSSSPVNNEPDKEDLEPEIRIVNGKPKKVRKPRTIYSSFQLAALQRRFQKTQYL 180 181 ALPERAELAASLGLTQTQVKIWFQNRRSKFKKMWKSGEIPTEQHPGASASPPCASPPVSA 240 241 PASWDFGAPQRMAGGGPGSGGGGAGSSGSSPSSAASAFLGNYPWYHQASGSASHLQATAP 300 301 LLHPSQTPQAHHHHHHHHHAGGGAPVSAGTIF |
| Interface Residues: | 156, 157, 158, 159, 197, 198, 200, 201, 204, 205, 208, 209, 212 |
| 3D-footprint Homologues: | 1puf_A, 1ig7_A, 5zjt_E, 3cmy_A, 1mnm_C, 6a8r_A, 3d1n_M, 1fjl_B, 5zfz_A, 2h1k_B, 2lkx_A, 1nk2_P, 1zq3_P, 6m3d_C, 7q3o_C, 6es3_K, 2ld5_A, 1b72_A, 5flv_I, 3lnq_A, 2hdd_A, 7psx_B, 5hod_A, 3rkq_B, 2r5y_A, 1jgg_B, 2hos_A, 5jlw_D, 4cyc_A, 4xrs_G, 4j19_B, 3a01_E, 1e3o_C, 2xsd_C, 1au7_A, 7xrc_C, 1le8_A, 8g87_X, 4qtr_D, 1du0_A, 1puf_B, 4xrm_B, 1k61_B, 3l1p_A, 1o4x_A |
| Binding Motifs: | MA0885.1 syAATTAw PH0021.1 vrdrYAATTRbhymag MA0885.2 awGCAATTAGmw MA0885.3 GCAATTAG |
| Binding Sites: | MA0885.3.20 MA0885.3.8 MA0885.2.1 / MA0885.2.4 MA0885.2.10 / MA0885.2.16 MA0885.2.11 / MA0885.2.19 MA0885.2.12 MA0885.2.13 MA0885.2.14 MA0885.2.15 MA0885.2.16 MA0885.2.17 MA0885.2.18 MA0885.2.19 MA0885.2.2 / MA0885.2.5 MA0885.2.20 MA0885.2.3 / MA0885.2.6 MA0885.2.4 / MA0885.2.8 MA0885.2.10 / MA0885.2.5 MA0885.2.12 / MA0885.2.6 MA0885.2.13 / MA0885.2.7 MA0885.2.14 / MA0885.2.8 MA0885.2.15 / MA0885.2.9 MA0885.2.1 MA0885.2.11 MA0885.2.17 MA0885.2.18 MA0885.2.2 MA0885.2.20 MA0885.2.3 MA0885.2.7 MA0885.2.9 MA0885.3.1 MA0885.3.10 MA0885.3.11 MA0885.3.12 / MA0885.3.13 MA0885.3.14 MA0885.3.15 / MA0885.3.3 MA0885.3.16 MA0885.3.17 MA0885.3.18 MA0885.3.19 MA0885.3.2 / MA0885.3.4 MA0885.3.5 MA0885.3.6 MA0885.3.7 / MA0885.3.9 |
| Publications: | Berger M.F, Badis G, Gehrke A.R, Talukder S, Philippakis A.A, Peña-Castillo L, Alleyne T.M, Mnaimneh S, Botvinnik O.B, Chan E.T, Khalid F, Zhang W, Newburger D, Jaeger S.A, Morris Q.D, Bulyk M.L, Hughes T.R. Variation in homeodomain DNA binding revealed by high-resolution analysis of sequence preferences. Cell 133:1266-76 (2008). [Pubmed] |
| Related annotations: | PaperBLAST |
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