Transcription Factor
| Accessions: | UP00244A (UniPROBE 20160601) |
| Names: | Enx, homeobox 2, Homeobox protein Hox-11L1, Homeobox TLX-2, Hox11L.1, Hox11l1, NCX, Ncx1, PMUR10F, T-cell leukemia, T-cell leukemia homeobox protein 2, Tlx1l1, Tlx1l2, Tlx2 |
| Organisms: | Mus musculus |
| Libraries: | UniPROBE 20160601 1 1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed] |
| Uniprot: | Q61663 |
| Description: | T-cell leukemia, homeobox 2 |
| Length: | 93 |
| Pfam Domains: | 17-73 Homeobox domain |
| Sequence: (in bold interface residues) | 1 TRRIGHPYQNRTPPKRKKPRTSFSRSQVLELERRFLRQKYLASAERAALAKALRMTDAQV 60 61 KTWFQNRRTKWRRQTAEEREAERHRAGRLLLHL |
| Interface Residues: | 6, 11, 17, 18, 19, 20, 58, 59, 61, 62, 65, 66, 69, 70, 73 |
| 3D-footprint Homologues: | 3a01_E, 3d1n_M, 1fjl_B, 2h1k_B, 1puf_A, 1ig7_A, 3cmy_A, 5zfz_A, 1nk2_P, 1zq3_P, 6m3d_C, 2lkx_A, 7q3o_C, 2ld5_A, 6es3_K, 5flv_I, 2hos_A, 5zjt_E, 4cyc_A, 1au7_A, 5hod_A, 3l1p_A, 6a8r_A, 1b72_A, 5jlw_D, 3lnq_A, 4xrs_G, 2hdd_A, 7psx_B, 3rkq_B, 2r5y_A, 1jgg_B, 1e3o_C, 2xsd_C, 7xrc_C, 1le8_A, 1k61_B, 6fqq_E, 1o4x_A, 4qtr_D, 8g87_X, 1mnm_C, 1du0_A, 1puf_B, 6fqp_B |
| Binding Motifs: | UP00244A_1 kwatyAATTAATaayww |
| Binding Sites: | ATTATAAT AATTAATA AATTAATT ATAATTAA ATAATTAT ATATTAAA ATCAATTA ATTAAAAA ATTAAATA ATTAATTA ATTAATTG ATTTAAAT ATTTAATA ATTTATAA CAATTAAA GCAATTAA TATTTAAA TCAATTAA TTAATTAA TTTTAAAA |
| Publications: | Berger M.F, Badis G, Gehrke A.R, Talukder S, Philippakis A.A, Peña-Castillo L, Alleyne T.M, Mnaimneh S, Botvinnik O.B, Chan E.T, Khalid F, Zhang W, Newburger D, Jaeger S.A, Morris Q.D, Bulyk M.L, Hughes T.R. Variation in homeodomain DNA binding revealed by high-resolution analysis of sequence preferences. Cell 133:1266-76 (2008). [Pubmed] |
| Related annotations: | PaperBLAST |
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.