DNA Binding Motif

Accessions: UP00133A_1 (UniPROBE 20160601)
Names: caudal type homeo box 2, Caudal-type homeobox protein 2, Cdx-2, Cdx2, Homeobox protein CDX-2
Organisms: Mus musculus
Libraries: UniPROBE 20160601 1
1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed]
Length: 16
Consensus: drvgGymATAAAayky
Weblogo:
PSSM: P0 A C G T
01 0.31 0.15 0.25 0.29 d
02 0.36 0.18 0.33 0.14 r
03 0.30 0.30 0.30 0.10 v
04 0.19 0.06 0.66 0.09 g
05 0.17 0.03 0.79 0 G
06 0 0.46 0 0.53 y
07 0.58 0.40 0 0.02 m
08 0.97 0 0.03 0 A
09 0.01 0 0 0.99 T
10 0.88 0 0 0.12 A
11 0.95 0 0 0.05 A
12 0.94 0.01 0 0.05 A
13 0.57 0.15 0.05 0.23 a
14 0.17 0.26 0.12 0.44 y
15 0.14 0.11 0.26 0.49 k
16 0.22 0.30 0.13 0.35 y
Binding TFs: UP00133A (Homeobox domain)
Binding Sites: TAATAAAA
AATAAAAT
AATAAACC
ACCATAAA
ATAATAAA
ATCATAAA
ATTTATGA
ATTTATGG
ATTTATTA
CAATAAAA
CAATAAAC
CCATAAAA
GCAATAAA
GCAATTAA
GCCATAAA
GTCATAAA
GTCGTAAA
GTTTATTA
TCAATAAA
TCATAAAA
Publications: Berger M.F, Badis G, Gehrke A.R, Talukder S, Philippakis A.A, Peña-Castillo L, Alleyne T.M, Mnaimneh S, Botvinnik O.B, Chan E.T, Khalid F, Zhang W, Newburger D, Jaeger S.A, Morris Q.D, Bulyk M.L, Hughes T.R. Variation in homeodomain DNA binding revealed by high-resolution analysis of sequence preferences. Cell 133:1266-76 (2008). [Pubmed]

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