DNA Binding Motif

Accessions: UP00166A_1 (UniPROBE 20160601)
Names: Bar-class homeodomain protein MBH2, BarH-like 1 (Drosophila), BarH-like 1 homeobox protein, BarH-related homeobox protein 1, Barhl1, Bhx1, Dres115
Organisms: Mus musculus
Libraries: UniPROBE 20160601 1
1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed]
Length: 16
Consensus: aamAAcCAATTArkwc
Weblogo:
PSSM: P0 A C G T
01 0.47 0.21 0.14 0.18 a
02 0.61 0.12 0.14 0.13 a
03 0.28 0.42 0.13 0.17 m
04 0.75 0.07 0.14 0.05 A
05 0.72 0.02 0.22 0.03 A
06 0.08 0.61 0.18 0.13 c
07 0.01 0.76 0 0.23 C
08 0.95 0.01 0.03 0.01 A
09 0.89 0.01 0 0.10 A
10 0 0 0 0.99 T
11 0.01 0.01 0 0.99 T
12 0.98 0 0 0.02 A
13 0.55 0.03 0.33 0.09 r
14 0.12 0.19 0.33 0.36 k
15 0.27 0.18 0.23 0.32 w
16 0.22 0.42 0.14 0.22 c
Binding TFs: UP00166A (Homeobox domain)
Binding Sites: AACAATTA
ACCAATTA
ACCGTTTA
ACTAATTG
AGCAATTA
ATAAACGG
ATAATTGG
ATCAATTA
CAATTAAC
CAATTAGC
CAATTAGG
CCAATTAA
CCAATTAG
CCGTTTAA
CCGTTTAG
CGTTTAGC
CTAATTGC
GACAATTA
GCAATTAA
GGCAATTA
Publications: Berger M.F, Badis G, Gehrke A.R, Talukder S, Philippakis A.A, Peña-Castillo L, Alleyne T.M, Mnaimneh S, Botvinnik O.B, Chan E.T, Khalid F, Zhang W, Newburger D, Jaeger S.A, Morris Q.D, Bulyk M.L, Hughes T.R. Variation in homeodomain DNA binding revealed by high-resolution analysis of sequence preferences. Cell 133:1266-76 (2008). [Pubmed]

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