Transcription Factor
| Accessions: | UP00157A (UniPROBE 20160601) |
| Names: | H6 homeo box 3, Hmx3, Homeobox protein HMX3, Homeobox protein Nkx-5.1, Nkx5-1, Nkx5.1 |
| Organisms: | Mus musculus |
| Libraries: | UniPROBE 20160601 1 1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed] |
| Description: | H6 homeo box 3 |
| Length: | 93 |
| Pfam Domains: | 17-73 Homeobox domain |
| Sequence: (in bold interface residues) | 1 WKAGAESPEKKPACRKKKTRTVFSRSQVFQLESTFDMKRYLSSSERAGLAASLHLTETQV 60 61 KIWFQNRRNKWKRQLAAELEAANLSHAAAQRIV |
| Interface Residues: | 11, 16, 17, 18, 19, 20, 45, 48, 49, 58, 59, 61, 62, 65, 66, 69, 70, 73 |
| 3D-footprint Homologues: | 5zfz_A, 3a01_E, 3d1n_M, 2h1k_B, 1puf_A, 1ig7_A, 6a8r_A, 3cmy_A, 1fjl_B, 1zq3_P, 3lnq_A, 2lkx_A, 1jgg_B, 1nk2_P, 6m3d_C, 6es3_K, 2ld5_A, 7q3o_C, 1b72_A, 5flv_I, 2hos_A, 7psx_B, 4cyc_A, 5hod_A, 3l1p_A, 5zjt_E, 5jlw_D, 1au7_A, 4xrs_G, 2hdd_A, 3rkq_B, 2r5y_A, 5uc6_A, 1ic8_B, 2xsd_C, 1le8_A, 2h8r_B, 1e3o_C, 7xrc_C, 8g87_X, 1k61_B, 1o4x_A, 6fqp_B, 1du0_A, 4qtr_D, 1mnm_C, 6fqq_E, 1puf_B |
| Binding Motifs: | UP00157A_1 asaAgCAATTAAwrrat |
| Binding Sites: | AATCAATT ACAATTAA ACCAATTA AGCAATTA ATAATTGA ATAATTGC ATCAATTA ATTAAGTG ATTAATTG CAATTAAA CAATTAAC CAATTAAG CAATTATA CCAATTAA CCACTTAA GACAATTA GCAATTAA GGCAATTA TAATTGCA TCAATTAA |
| Publications: | Berger M.F, Badis G, Gehrke A.R, Talukder S, Philippakis A.A, Peña-Castillo L, Alleyne T.M, Mnaimneh S, Botvinnik O.B, Chan E.T, Khalid F, Zhang W, Newburger D, Jaeger S.A, Morris Q.D, Bulyk M.L, Hughes T.R. Variation in homeodomain DNA binding revealed by high-resolution analysis of sequence preferences. Cell 133:1266-76 (2008). [Pubmed] |
| Related annotations: | PaperBLAST |
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