Transcription Factor

Accessions: UP00259A (UniPROBE 20160601)
Names: homeo box B6, Homeobox protein Hox-B6, Hox-2.2, Hoxb-6, Hoxb6, MH-22A
Organisms: Mus musculus
Libraries: UniPROBE 20160601 1
1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed]
Uniprot: P09023
Description: homeo box B6
Length: 93
Pfam Domains: 17-73 Homeobox domain
Sequence:
(in bold interface residues)
1 MQRMNSCNSSSFGPSGRRGRQTYTRYQTLELEKEFHYNRYLTRRRRIEIAHALCLTERQI 60
61 KIWFQNRRMKWKKESKLLSASQLSAEEEEEKPA
Interface Residues: 17, 18, 19, 20, 21, 58, 59, 61, 62, 65, 66, 69, 70, 73
3D-footprint Homologues: 1ig7_A, 6a8r_A, 2h1k_B, 1puf_A, 3cmy_A, 5zfz_A, 1fjl_B, 1zq3_P, 1jgg_B, 3lnq_A, 2lkx_A, 6m3d_C, 3d1n_M, 2ld5_A, 1nk2_P, 4cyc_A, 7psx_B, 5hod_A, 3a01_E, 7q3o_C, 5jlw_D, 6es3_K, 4xrs_G, 2hdd_A, 3rkq_B, 1puf_B, 5flv_I, 2hos_A, 1b72_A, 5zjt_E, 2r5y_A, 2xsd_C, 1e3o_C, 1le8_A, 7xrc_C, 3l1p_A, 1o4x_A, 1du0_A, 4qtr_D, 8g87_X
Binding Motifs: UP00259A_1 wwtksgTAATTACsdy
Binding Sites: GGTAATTA
AATAATTA
AATTAATA
ACTAATTA
AGTAATTA
ATAATTAA
ATAATTAC
ATTAATGA
ATTAATTA
CATTAATG
CCATTAAC
CCCATTAA
GCAATTAA
GCCATTAA
GTAATTAA
GTAATTAC
GTCATTAA
GTTAATTA
TAATTATA
TAATTGCA
Publications: Berger M.F, Badis G, Gehrke A.R, Talukder S, Philippakis A.A, Peña-Castillo L, Alleyne T.M, Mnaimneh S, Botvinnik O.B, Chan E.T, Khalid F, Zhang W, Newburger D, Jaeger S.A, Morris Q.D, Bulyk M.L, Hughes T.R. Variation in homeodomain DNA binding revealed by high-resolution analysis of sequence preferences. Cell 133:1266-76 (2008). [Pubmed]
Related annotations: PaperBLAST

Disclaimer and license

These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.