DNA Binding Site

						

			
Accessions: en_20-2-B (DrosophilaTF 1.1), TAATTATA (UniPROBE 20160601)

			
Organisms: Drosophila melanogaster, Mus musculus, Saccharomyces cerevisiae, Homo sapiens
Libraries: DrosophilaTF 1.1 1, UniPROBE 20160601 2
1 Down T.A, Bergman C.M, Su J, Hubbard T.J. Large-scale discovery of promoter motifs in Drosophila melanogaster. PLoS computational biology 3:e7 (2007). [Pubmed]

2 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed]
Length: 8
Sequence: TAATTATA
Type: Heterodimer
Binding TFs: UP00352A (HMG (high mobility group) box, Domain of unknown function (DUF1898))
UP00263A (Homeobox domain)
en (Homeobox domain, Engrailed homeobox C-terminal signature domain)
UP00110A (Homeobox domain)
UP00113A (Homeobox domain)
UP00123A (Homeobox domain)
UP00126A (Homeobox domain)
UP00130A (Homeobox domain, Homeobox KN domain)
UP00141A (Homeobox domain)
UP00154A (Homeobox domain)
UP00167A (Homeobox domain, Engrailed homeobox C-terminal signature domain)
UP00168A (Homeobox domain)
UP00172A (Homeobox domain, Homeobox KN domain)
UP00200A (Homeobox domain)
UP00202A (Homeobox domain)
UP00206A (Homeobox domain)
UP00212A (Homeobox domain, Homeobox KN domain)
UP00221A (Homeobox domain)
UP00230A (Homeobox domain)
UP00234A (Homeobox domain)
UP00237A (Homeobox domain)
UP00248A (Homeobox domain, 'Paired box' domain, Homeobox KN domain)
UP00255A (Homeobox domain)
UP00259A (Homeobox domain)
UP00262A (Homeobox domain, Homeobox KN domain)
UP00294A (SRF-type transcription factor (DNA-binding and dimerisation domain))
UP00164A (Homeobox domain)
UP00584B (Homeobox domain)
UP00584D (Homeobox domain)
UP00585B (Zinc finger, C2H2 type, Zinc-finger of C2H2 type, Zinc-finger double domain, C2H2-type zinc finger, C2H2-type zinc finger)
UP00594D (Homeobox domain)
UP00595A (Homeobox domain)
UP00595B (Homeobox domain)
UP00595C (Homeobox domain)
UP00596A (Homeobox domain)
UP00596B (Homeobox domain)
UP00596C (Homeobox domain)
UP00603B (Homeobox domain)
UP00604D (Homeobox domain)
UP00604E (Homeobox domain)
UP00610B (Homeobox domain, 'Paired box' domain)
UP00611D (Homeobox domain, 'Paired box' domain)
UP00616C (Homeobox domain, Pou domain - N-terminal to homeobox domain)
UP00616E (Homeobox domain, Pou domain - N-terminal to homeobox domain)
UP00618C (Homeobox domain, Pou domain - N-terminal to homeobox domain)
UP00626C (Homeobox domain)
Binding Motifs: UP00259A_1 wwtksgTAATTACsdy
UP00200A_2 rrtwATTAATKAykyc
UP00255A_1 twrttaATTAwtaawwr
UP00110A_1 bcrcdaTAATTAcmswc
UP00113A_1 CgmrTTAATTAAywawm
UP00123A_1 kkmsTAATTAGkgshv
UP00126A_1 vrdrYAATTRbhymag
UP00130A_1 sdaaTTAATTAAwwmmk
UP00141A_1 csaryTAATTAryratt
UP00154A_1 kmrmdaTAATTAcmswm
UP00164A_1 sgmrtTAATTAatwagc
UP00167A_1 gsvAAcTAATTArkgc
UP00168A_1 taadTAATTAATrgctw
UP00172A_1 cgmrTTAATTAAkwdac
UP00200A_1 gmwwATTAATTAmyybg
UP00202A_1 btgarrTAATTAay
UP00206A_1 stakTAATTAmtkshr
UP00212A_1 sraaTTAATTAAwwamy
UP00221A_1 yrkmAyTAATTAryrv
UP00230A_1 ssrgyAATTrsykmts
UP00234A_1 krmwayTAATTAatwm
UP00237A_1 cryarTTAATTAAykkg
UP00248A_1 mgwmyTAATTArkwmda
UP00262A_1 mgwaTTAATTAAwwahk
UP00263A_1 wsykGyAATTAAtarw
UP00294A_1 tkacctwtAATTawaybwsmw
UP00352A_1 mtkwhywmTATATAawwwwrh
en TAATTa
UP00164A_2 kkmkTAATTAmkggmm
UP00584B_2 wtwhtddkmTAATTAvmshwkrw
UP00584D_1 Trrkdgbayaattrtwrmtwdw
UP00585B_1 wywmtskkyTAATTAhmmkrkda
UP00594D_1 yagmhskaymwraawmsmcwaw
UP00595A_1 TdanrbbrTAATTAytrywawww
UP00595A_2 ttmyywrrTAATTAyyawtwwA
UP00595B_1 wamktwTAATywATTAtartttt
UP00595B_2 ttmyyargTAATTAcydwtwwA
UP00595C_1 TwasksyATAATTAtwGgtwkdr
UP00596A_1 rAawwaATAATmATTAkycwwwr
UP00596B_2 twmmwasyTAATTArtwawadk
UP00596C_2 wtmtawGkTAATTAhChhAdwaa
UP00603B_1 wtwtrtgyAATTAwttaaktysw
UP00604D_1 amaTtawatavrtatwywaTwa
UP00604E_1 tawwywATrTwwATtAwytaAA
UP00610B_1 twwwkcbkttTAATTAasmasgk
UP00611D_1 whwydkgkTAATTAkcawawwaw
UP00616C_1 kgacgyyyTAATTArwcrtcrr
UP00616E_1 kgmcgyyyTAATTArwcakcrg
UP00618C_1 twwmrybagcTAATTArbrywmt
UP00626C_1 tmmmamvTTAATTAAkwrtmtg
			
Publications: Ades S.E, Sauer R.T. Differential DNA-binding specificity of the engrailed homeodomain: the role of residue 50. Biochemistry 33:9187-94 (1994). [Pubmed]


Berger M.F, Badis G, Gehrke A.R, Talukder S, Philippakis A.A, Peña-Castillo L, Alleyne T.M, Mnaimneh S, Botvinnik O.B, Chan E.T, Khalid F, Zhang W, Newburger D, Jaeger S.A, Morris Q.D, Bulyk M.L, Hughes T.R. Variation in homeodomain DNA binding revealed by high-resolution analysis of sequence preferences. Cell 133:1266-76 (2008). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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