Transcription Factor
| Accessions: | UP00264A (UniPROBE 20160601) |
| Names: | early retinoic acid, Early retinoic acid 1, Era-1, ERA1, homeo box A1, Homeobox protein Hox-A1, Homeoboxless protein ERA-1-399, Homeotic protein ERA-1-993, Hox-1.6, Hoxa-1, Hoxa1 |
| Organisms: | Mus musculus |
| Libraries: | UniPROBE 20160601 1 1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed] |
| Uniprot: | P09022 |
| Description: | homeo box A1 |
| Length: | 93 |
| Pfam Domains: | 20-73 Homeobox domain |
| Sequence: (in bold interface residues) | 1 PPKTGKVGEYGYVGQPNAVRTNFTTKQLTELEKEFHFNKYLTRARRVEIAASLQLNETQV 60 61 KIWFQNRRMKQKKREKEGLLPISPATPPGSDEK |
| Interface Residues: | 18, 19, 20, 21, 58, 59, 61, 62, 65, 66, 69, 70, 73 |
| 3D-footprint Homologues: | 2lkx_A, 1zq3_P, 6es3_K, 1puf_A, 6a8r_A, 3cmy_A, 2hdd_A, 7q3o_C, 5jlw_D, 3rkq_B, 2r5y_A, 1puf_B, 1fjl_B, 4xrs_G, 3d1n_M, 2hos_A, 5zfz_A, 1b72_A, 4cyc_A, 6m3d_C, 1ig7_A, 5flv_I, 3a01_E, 2h1k_B, 7psx_B, 1jgg_B, 5hod_A, 3lnq_A, 1nk2_P, 2ld5_A, 1e3o_C, 1le8_A, 1au7_A, 7xrc_C, 2xsd_C, 4j19_B, 4qtr_D, 3l1p_A, 8g87_X, 1o4x_A, 5zjt_E, 1du0_A |
| Binding Motifs: | UP00264A_3 wwwbCTCGTAAAawtt UP00264A_1 dmgGyMATWAAAtkmw UP00264A_2 waarGTCRTAAAayrk UP00264A_4 ctrarcTAATTAmyky |
| Binding Sites: | TAATAAAA AATAAAAT AATTAATA ATAATAAA ATTAATTA ATTTTATG CAATAAAA CCATAAAA GCAATAAA GCAATTAA GTAATAAA GTAATTAA GTCATAAA GTCATTAA GTCGTAAA TAATTAAA TCATAAAA TCATTAAA TCGTAAAA TTAATTAA |
| Publications: | Berger M.F, Badis G, Gehrke A.R, Talukder S, Philippakis A.A, Peña-Castillo L, Alleyne T.M, Mnaimneh S, Botvinnik O.B, Chan E.T, Khalid F, Zhang W, Newburger D, Jaeger S.A, Morris Q.D, Bulyk M.L, Hughes T.R. Variation in homeodomain DNA binding revealed by high-resolution analysis of sequence preferences. Cell 133:1266-76 (2008). [Pubmed] |
| Related annotations: | PaperBLAST |
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.