DNA Binding Motif

						

			
Accessions: UP00157A_1 (UniPROBE 20160601)

			
Names: H6 homeo box 3, Hmx3, Homeobox protein HMX3, Homeobox protein Nkx-5.1, Nkx5-1, Nkx5.1
Organisms: Mus musculus
Libraries: UniPROBE 20160601 1
1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed]
Length: 17
Consensus: asaAgCAATTAAwrrat
Weblogo: 
PSSM: P0      A      C      G      T
01   0.49   0.21   0.21   0.09      a
02   0.12   0.49   0.25   0.13      s
03   0.48   0.23   0.19   0.10      a
04   0.76   0.07   0.11   0.06      A
05   0.15   0.10   0.59   0.15      g
06   0.02   0.94      0   0.04      C
07   0.84      0   0.16   0.01      A
08   0.87   0.12      0   0.01      A
09   0.01      0      0   0.99      T
10   0.01   0.04      0   0.94      T
11   0.92      0   0.02   0.05      A
12   0.87   0.02   0.03   0.07      A
13   0.39   0.15   0.12   0.35      w
14   0.26   0.18   0.38   0.18      r
15   0.47   0.21   0.26   0.06      r
16   0.52   0.11   0.18   0.19      a
17   0.13   0.10   0.13   0.64      t
Binding TFs: UP00157A (Homeobox domain)
Binding Sites: AATCAATT
ACAATTAA
ACCAATTA
AGCAATTA
ATAATTGA
ATAATTGC
ATCAATTA
ATTAAGTG
ATTAATTG
CAATTAAA
CAATTAAC
CAATTAAG
CAATTATA
CCAATTAA
CCACTTAA
GACAATTA
GCAATTAA
GGCAATTA
TAATTGCA
TCAATTAA
			
Publications: Berger M.F, Badis G, Gehrke A.R, Talukder S, Philippakis A.A, Peña-Castillo L, Alleyne T.M, Mnaimneh S, Botvinnik O.B, Chan E.T, Khalid F, Zhang W, Newburger D, Jaeger S.A, Morris Q.D, Bulyk M.L, Hughes T.R. Variation in homeodomain DNA binding revealed by high-resolution analysis of sequence preferences. Cell 133:1266-76 (2008). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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