DNA Binding Motif

						

			
Accessions: UP00139A_1 (UniPROBE 20160601)

			
Names: Homeobox protein SAX-1, locus 2 (Drosophila), NK1 transcription factor related, NK1 transcription factor-related protein 2, Nkx-1.1, Nkx-1.2, Nkx1-2, Nkx1.1, Sax1
Organisms: Mus musculus
Libraries: UniPROBE 20160601 1
1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed]
Length: 17
Consensus: dtbcryYAATTRrtrcw
Weblogo: 
PSSM: P0      A      C      G      T
01   0.26   0.16   0.30   0.29      d
02   0.19   0.16   0.23   0.43      t
03   0.12   0.25   0.35   0.28      b
04   0.20   0.50   0.18   0.13      c
05   0.48   0.07   0.40   0.06      r
06   0.11   0.47   0.07   0.35      y
07   0.02   0.30      0   0.68      Y
08   0.93   0.06      0      0      A
09   0.96      0      0   0.04      A
10   0.04      0      0   0.96      T
11      0      0   0.06   0.93      T
12   0.68      0   0.30   0.02      R
13   0.35   0.07   0.47   0.11      r
14   0.11   0.15   0.18   0.56      t
15   0.28   0.15   0.34   0.23      r
16   0.10   0.57   0.20   0.14      c
17   0.56   0.05   0.02   0.36      w
Binding TFs: UP00139A (Homeobox domain)
Binding Sites: GGTAATTA
AATAATTA
ACCAATTA
ACTAATTA
AGTAATTA
ATAATTAC
ATAATTAG
ATTAATTA
CCAATTAG
CCTAATTA
CTAATTAA
CTAATTAC
CTAATTGC
CTTAATTA
GATAATTA
GCAATTAA
GCTAATTA
GTAATTAC
GTTAATTA
TTAATTAA
			
Publications: Berger M.F, Badis G, Gehrke A.R, Talukder S, Philippakis A.A, Peña-Castillo L, Alleyne T.M, Mnaimneh S, Botvinnik O.B, Chan E.T, Khalid F, Zhang W, Newburger D, Jaeger S.A, Morris Q.D, Bulyk M.L, Hughes T.R. Variation in homeodomain DNA binding revealed by high-resolution analysis of sequence preferences. Cell 133:1266-76 (2008). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.