DNA Binding Site
| Accessions: | TCAATAAA (UniPROBE 20160601), MA0465.3.13 (JASPAR 2024), MA0465.3.15 (JASPAR 2024), MA0465.3.4 (JASPAR 2024), MA0650.4.18 (JASPAR 2024), MA0650.4.19 (JASPAR 2024) |
| Organisms: | Mus musculus, Homo sapiens |
| Libraries: | UniPROBE 20160601 1, JASPAR 2024 2 1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed] 2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Length: | 8 |
| Sequence: | TCAATAAA |
| Type: | Heterodimer |
| Binding TFs: | Q62424 (Homeobox domain, Hox protein A13 N terminal) UP00133A (Homeobox domain) UP00173A (Homeobox domain, Homeobox KN domain) UP00180A (Homeobox domain) Q99626 (Homeobox domain, Caudal like protein activation region) UP00597B (Homeobox domain) UP00597G (Homeobox domain) UP00597H (Homeobox domain) Q62424 Q99626 |
| Binding Motifs: | UP00133A_1 drvgGymATAAAayky UP00173A_1 wwwkCTCrTAAAawtw UP00180A_1 mwwyyAATAAAAhymh UP00597B_1 tksmrytyaATAAAAwwcdmtt UP00597G_1 wwtaaryYAATAAAAwtcwmww UP00597G_2 wrkmrayYAATAAAAwwcwmtt UP00597H_1 kksmrcyyAATAAAAwwmavtt MA0465.3 GCAATAAA MA0650.4 CCAATAAA |
| Publications: | Berger M.F, Badis G, Gehrke A.R, Talukder S, Philippakis A.A, Peña-Castillo L, Alleyne T.M, Mnaimneh S, Botvinnik O.B, Chan E.T, Khalid F, Zhang W, Newburger D, Jaeger S.A, Morris Q.D, Bulyk M.L, Hughes T.R. Variation in homeodomain DNA binding revealed by high-resolution analysis of sequence preferences. Cell 133:1266-76 (2008). [Pubmed] Verzi M.P, Hatzis P, Sulahian R, Philips J, Schuijers J, Shin H, Freed E, Lynch J.P, Dang D.T, Brown M, Clevers H, Liu X.S, Shivdasani R.A. TCF4 and CDX2, major transcription factors for intestinal function, converge on the same cis-regulatory regions. Proceedings of the National Academy of Sciences of the United States of America 107:15157-62 (2010). [Pubmed] Knosp W. M., Saneyoshi C., Shou S., Bachinger H. P., Stadler H. S. Elucidation, quantitative refinement, and in vivo utilization of the HOXA13 DNA binding site.. J. Biol. Chem. 282:6843-6853 (2007). [Pubmed] |
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