Transcription Factor

Accessions: UP00183A (UniPROBE 20160601)
Names: Hd, homeo box A13, Homeobox protein Hox-A13, Hox-1.10, Hoxa13, MGC124020, MGC124021, MGC124022
Organisms: Mus musculus
Libraries: UniPROBE 20160601 1
1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed]
Uniprot: PQ6242
Description: homeo box A13
Length: 82
Pfam Domains: 17-73 Homeobox domain
Sequence:
(in bold interface residues)
1 PDVVSHPSDASSYRRGRKKRVPYTKVQLKELEREYATNKFITKDKRRRISATTNLSERQV 60
61 TIWFQNRRVKEKKVINKLKTTS
Interface Residues: 17, 18, 19, 20, 58, 59, 61, 62, 65, 66, 69, 70, 73
3D-footprint Homologues: 3d1n_M, 6a8r_A, 1fjl_B, 2h1k_B, 5zfz_A, 1puf_A, 1ig7_A, 3cmy_A, 1nk2_P, 1zq3_P, 2lkx_A, 7q3o_C, 2ld5_A, 6es3_K, 5hod_A, 2hos_A, 5jlw_D, 3lnq_A, 4xrs_G, 3a01_E, 1b72_A, 3rkq_B, 6m3d_C, 5flv_I, 2hdd_A, 5zjt_E, 4cyc_A, 2r5y_A, 1puf_B, 1jgg_B, 7psx_B, 1e3o_C, 2xsd_C, 1au7_A, 1le8_A, 7xrc_C, 4qtr_D, 1k61_B, 1o4x_A, 1mnm_C, 1du0_A
Binding Motifs: UP00183A_1 wwwbCTCGTAAAawtt
Binding Sites: TAATAAAA
AATAAAAA
AATAAAAC
AATAAAAT
ATTTACGA
CAATAAAA
CCAATAAA
CCATAAAA
CCCATAAA
CCTATAAA
CTAATAAA
CTATAAAA
CTCATAAA
CTCGTTAA
GCAATAAA
GTCGTAAA
GTTTACGA
TCATAAAA
TCGTAAAA
CTTGTAAA
Publications: Berger M.F, Badis G, Gehrke A.R, Talukder S, Philippakis A.A, Peña-Castillo L, Alleyne T.M, Mnaimneh S, Botvinnik O.B, Chan E.T, Khalid F, Zhang W, Newburger D, Jaeger S.A, Morris Q.D, Bulyk M.L, Hughes T.R. Variation in homeodomain DNA binding revealed by high-resolution analysis of sequence preferences. Cell 133:1266-76 (2008). [Pubmed]
Related annotations: PaperBLAST

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.