Transcription Factor
| Accessions: | UP00503A (UniPROBE 20160601) |
| Names: | Abd B, Abd-B, Abd0B, abdB, AbdB-I, AbdB-II, AbdB(CA)[[26]], Abdominal B, AdbB, bex, BX-C, CG10291, CG11648, DmAbdB, Dmel\CG11648, Droabdb, FAB, Fab-7, Fab-8, Fab7, Homeobox protein abdominal-B, iab, IAB 5, iab-5, iab-6, iab-7, iab-8, iab5, iab6, iab7, iab8, iab8.9, iab9, Infraabdominal 7, l(3)89Ed, Mc, Mcp, P3, pH189, Sab, Tab, tuh-3, twig, Uab-5[Sab] |
| Organisms: | Drosophila melanogaster |
| Libraries: | UniPROBE 20160601 1 1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed] |
| Description: | Abdominal B: The Abdominal-B gene, a member of the Drosophila bithorax complex, is required during development to specify the identity of parasegments 10-14. |
| Length: | 83 |
| Pfam Domains: | 16-72 Homeobox domain |
| Sequence: (in bold interface residues) | 1 TPNPGLHEWTGQVSVRKKRKPYSKFQTLELEKEFLFNAYVSKQKRWELARNLQLTERQVK 60 61 IWFQNRRMKNKKNSQRQANQQNN |
| Interface Residues: | 16, 17, 18, 19, 20, 56, 57, 58, 60, 61, 64, 65, 68, 69, 72 |
| 3D-footprint Homologues: | 2h1k_B, 1puf_A, 3cmy_A, 5zfz_A, 1fjl_B, 1ig7_A, 6a8r_A, 2lkx_A, 3d1n_M, 1nk2_P, 1zq3_P, 6es3_K, 2ld5_A, 7q3o_C, 3a01_E, 5jlw_D, 3lnq_A, 1jgg_B, 4xrs_G, 2hdd_A, 6m3d_C, 3rkq_B, 2r5y_A, 1puf_B, 1au7_A, 2hos_A, 7psx_B, 5zjt_E, 4cyc_A, 1b72_A, 3l1p_A, 6cqi_A, 7xrc_C, 1e3o_C, 2xsd_C, 1le8_A, 1le8_B, 6fqq_E, 1du0_A, 1mnm_C, 8g87_X, 1k61_B, 5flv_I, 6fqp_B, 5hod_A, 1o4x_A, 4qtr_D, 8him_B |
| Binding Motifs: | UP00503A_1 ggrarrgGymATWAAattyhba |
| Binding Sites: | TAATAAAA GGTAATTA ATTAATTA ATTTTATG CAATAAAA CCATAAAA CCCATAAA GCAATAAA GCCATAAA GTAATAAA GTAATTAA GTAATTAC GTCATAAA GTCATTAA GTCGTAAA TAATTAAA TCATAAAA ACATAAAA CCATTAAA GCTATAAA |
| Publications: | Busser BW, Shokri L, Jaeger SA, Gisselbrecht SS, Singhania A, Berger MF, Zhou B, Bulyk ML, Michelson AM. Molecular mechanism underlying the regulatory specificity of a Drosophila homeodomain protein that specifies myoblast identity. Development 139:1164-74 (2012). [Pubmed] |
| Related annotations: | PaperBLAST |
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