Transcription Factor
| Accessions: | UP00115A (UniPROBE 20160601) |
| Names: | ap, apterous, Lh-2, LH2A, Lhx2, LIM homeobox protein 2, LIM/homeobox protein Lhx2, Lim2 |
| Organisms: | Mus musculus |
| Libraries: | UniPROBE 20160601 1 1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed] |
| Uniprot: | Q9Z0S2 |
| Description: | LIM homeobox protein 2 |
| Length: | 93 |
| Pfam Domains: | 6-69 Homeobox KN domain 17-73 Homeobox domain |
| Sequence: (in bold interface residues) | 1 AEHLDRDQPYPSSQKTKRMRTSFKHHQLRTMKSYFAINHNPDAKDLKQLAQKTGLTKRVL 60 61 QVWFQNARAKFRRNLLRQENTGVDKTSDATLQT |
| Interface Residues: | 6, 7, 16, 17, 18, 19, 20, 58, 59, 61, 62, 65, 66, 69, 70, 72, 73 |
| 3D-footprint Homologues: | 5c8e_C, 3d1n_M, 6a8r_A, 1puf_A, 2h1k_B, 1fjl_B, 5zfz_A, 3cmy_A, 1zq3_P, 1nk2_P, 1jgg_B, 6m3d_C, 3lnq_A, 2lkx_A, 2r5y_A, 7q3o_C, 2ld5_A, 6es3_K, 1ig7_A, 5zjt_E, 2hos_A, 5hod_A, 4cyc_A, 2d5v_B, 4xrs_G, 3l1p_A, 5jlw_D, 4j19_B, 3a01_E, 1puf_B, 7psx_B, 2hdd_A, 1b72_A, 5flv_I, 3rkq_B, 2xsd_C, 7xrc_C, 1e3o_C, 1le8_A, 6fqq_E, 1du0_A, 8g87_X, 4qtr_D, 1le8_B, 6fqp_B, 4xrm_B |
| Binding Motifs: | UP00115A_1 waaayTAATTArykmhs |
| Binding Sites: | AATAATTA AATTAATT ACTAATTA ATAATTAA ATAATTAG ATAATTGG ATTAATTA CCAATTAA CCAATTAG CCTAATTA CTAATTAA CTTAATTA GATAATTA GCCAATTA GCTAATTA GTAATTAA GTTAATTA TAATTAAA TAATTAGA TTAATTAA |
| Publications: | Berger M.F, Badis G, Gehrke A.R, Talukder S, Philippakis A.A, Peña-Castillo L, Alleyne T.M, Mnaimneh S, Botvinnik O.B, Chan E.T, Khalid F, Zhang W, Newburger D, Jaeger S.A, Morris Q.D, Bulyk M.L, Hughes T.R. Variation in homeodomain DNA binding revealed by high-resolution analysis of sequence preferences. Cell 133:1266-76 (2008). [Pubmed] |
| Related annotations: | PaperBLAST |
Disclaimer and license
These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.