Transcription Factor

Accessions: UP00268A (UniPROBE 20160601)
Names: BAS2, D2350, General regulatory factor 10, GRF10, Pho2, Regulatory protein PHO2, YDL106C
Organisms: Saccharomyces cerevisiae
Libraries: UniPROBE 20160601 1
1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed]
Uniprot: P07269
Description: Homeobox transcription factor; regulatory targets include genes involved in phosphate metabolism; binds cooperatively with Pho4p to the PHO5 promoter; phosphorylation of Pho2p facilitates interaction
Length: 157
Pfam Domains: 51-107 Homeobox domain
Sequence:
(in bold interface residues)
1 QQQQQQHDQQHNQQQQPQPQPIQTQNLEHDHDQHTNDMSASSNASDSGPQRPKRTRAKGE 60
61 ALDVLKRKFEINPTPSLVERKKISDLIGMPEKNVRIWFQNRRAKLRKKQHGSNKDTIPSS 120
121 QSRDIANDYDRGSTDNNLVTTTSTSSIFHDEDLTFFD
Interface Residues: 50, 51, 52, 53, 54, 56, 92, 93, 95, 96, 99, 100, 103, 104, 107
3D-footprint Homologues: 4j19_B, 1puf_A, 6a8r_A, 3cmy_A, 1fjl_B, 3d1n_M, 6m3d_C, 2lkx_A, 2h1k_B, 3rkq_B, 4cyc_A, 5hod_A, 2hdd_A, 1au7_A, 1puf_B, 2hos_A, 1nk2_P, 3l1p_A, 5jlw_D, 2ld5_A, 1e3o_C, 1le8_A, 7q3o_C, 7xrc_C, 2xsd_C, 1ig7_A, 1o4x_A, 8g87_X, 1du0_A, 5zjt_E, 3a01_E, 1jgg_B, 7psx_B, 3lnq_A, 4qtr_D, 2r5y_A, 6es3_K, 4xrs_G, 1b72_A, 5zfz_A, 1zq3_P, 5flv_I
Binding Motifs: UP00268A_1 cgyddwtTAATTAawksgrm
Binding Sites: AAATTAAT
AATAATTA
AATATATT
AATTAATA
AATTAATT
ATAAATTA
ATATATTA
ATATTAAT
ATTAATTA
CTAATTAA
GTAATAAA
GTAATATA
GTAATTTA
TAATATAA
TAATATTA
TAATTAAA
TAATTTAA
TATATTAA
TATTAATA
TTAATTAA
Publications: *Zhu C, *Byers K, *McCord RP, Shi Z, Berger MF, Newburger D, Saulrieta K, Smith Z, Shah M, Radhakrishnan M, Philippakis AA, Hu Y, De Masi F, Pacek M, Rolfs A , Murthy TVS, LaBaer J, Bulyk ML. High-Resolution DNA Binding Specificity Analysis of Yeast Transcription Factors. Genome Research. Epub January 21, 2009, doi:10.1101/gr.090233.108 (*co-1st authors). [Pubmed]
Related annotations: PaperBLAST

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.