Transcription Factor
| Accessions: | UP00172A (UniPROBE 20160601) |
| Names: | df, Homeobox protein prophet of Pit-1, paired like homeodomain factor 1, Pituitary-specific homeodomain factor, Prop-1, Prop1, prophet of Pit1 |
| Organisms: | Mus musculus |
| Libraries: | UniPROBE 20160601 1 1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed] |
| Uniprot: | P97458 |
| Description: | paired like homeodomain factor 1 |
| Length: | 93 |
| Pfam Domains: | 17-73 Homeobox domain 40-69 Homeobox KN domain |
| Sequence: (in bold interface residues) | 1 LGRPKLCPQRGRPHSRRRHRTTFNPAQLEQLESAFGRNQYPDIWAREGLAQDTGLSEARI 60 61 QVWFQNRRAKQRKQERSLLQPIAHLSTATFSGF |
| Interface Residues: | 16, 17, 18, 19, 20, 58, 59, 61, 62, 65, 66, 69, 70, 73, 76, 77 |
| 3D-footprint Homologues: | 4j19_B, 1puf_A, 5zfz_A, 1mnm_C, 1fjl_B, 3cmy_A, 6a8r_A, 3d1n_M, 1ig7_A, 2h1k_B, 1jgg_B, 3lnq_A, 2lkx_A, 1nk2_P, 1zq3_P, 6m3d_C, 2ld5_A, 7q3o_C, 1k61_B, 1le8_B, 6es3_K, 4xrs_G, 3l1p_A, 7psx_B, 1au7_A, 3a01_E, 2h8r_B, 5flv_I, 1puf_B, 5zjt_E, 1b72_A, 2hdd_A, 1ic8_B, 5hod_A, 3rkq_B, 2r5y_A, 2hos_A, 5jlw_D, 4cyc_A, 1e3o_C, 7xrc_C, 1le8_A, 2xsd_C, 6fqp_B, 4qtr_D, 6fqq_E, 1du0_A, 4xrm_B, 1o4x_A, 8g87_X |
| Binding Motifs: | UP00172A_1 cgmrTTAATTAAkwdac |
| Binding Sites: | AATAATTA AATTAATT ACCAATTA ACTAATTA AGTAATTA ATAATTAA ATAATTAG ATAATTAT ATTAATTA CCTAATTA CTAATTAA CTAATTAG CTTAATTA GATAATTA GCTAATTA GTAATTAA GTTAATTA TAATTAAA TAATTAGA TAATTATA |
| Publications: | Berger M.F, Badis G, Gehrke A.R, Talukder S, Philippakis A.A, Peña-Castillo L, Alleyne T.M, Mnaimneh S, Botvinnik O.B, Chan E.T, Khalid F, Zhang W, Newburger D, Jaeger S.A, Morris Q.D, Bulyk M.L, Hughes T.R. Variation in homeodomain DNA binding revealed by high-resolution analysis of sequence preferences. Cell 133:1266-76 (2008). [Pubmed] |
| Related annotations: | PaperBLAST |
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