DNA Binding Motif

Accessions: UP00218A_1 (UniPROBE 20160601)
Names: 9630005K15, AI846217, Dbx2, developing brain homeobox 2
Organisms: Mus musculus
Libraries: UniPROBE 20160601 1
1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed]
Length: 16
Consensus: bktmAtTAATkAakwm
Weblogo:
PSSM: P0 A C G T
01 0.14 0.27 0.27 0.33 b
02 0.24 0.09 0.32 0.35 k
03 0.22 0.24 0.20 0.33 t
04 0.44 0.29 0.04 0.22 m
05 0.70 0.07 0.08 0.15 A
06 0.18 0.12 0.10 0.61 t
07 0.06 0.12 0 0.82 T
08 0.93 0.01 0.02 0.04 A
09 0.95 0.01 0.02 0.02 A
10 0.03 0 0.01 0.96 T
11 0.03 0.02 0.29 0.67 k
12 0.73 0.01 0.15 0.11 A
13 0.44 0.11 0.20 0.24 a
14 0.04 0.09 0.28 0.59 k
15 0.27 0.16 0.14 0.43 w
16 0.28 0.35 0.17 0.20 m
Binding TFs: UP00218A (Homeobox domain)
Binding Sites: GGTAATTA
AAATTAAT
AATAATTA
AATTAATA
AATTAATG
AATTAATT
ACTAATTA
AGTAATTA
ATAATTAA
ATAATTAT
ATCAATTA
ATTAATGA
ATTAATTG
CATTAATG
CTAATTAA
CTAATTAG
GTAATTAA
GTAATTAC
TAATTAAA
TTAATTAA
Publications: Berger M.F, Badis G, Gehrke A.R, Talukder S, Philippakis A.A, Peña-Castillo L, Alleyne T.M, Mnaimneh S, Botvinnik O.B, Chan E.T, Khalid F, Zhang W, Newburger D, Jaeger S.A, Morris Q.D, Bulyk M.L, Hughes T.R. Variation in homeodomain DNA binding revealed by high-resolution analysis of sequence preferences. Cell 133:1266-76 (2008). [Pubmed]

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.