Transcription Factor
| Accessions: | UP00247A (UniPROBE 20160601) |
| Names: | paired box gene 4, Paired box protein Pax-4, Pax4 |
| Organisms: | Mus musculus |
| Libraries: | UniPROBE 20160601 1 1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed] |
| Uniprot: | P32115 |
| Description: | paired box gene 4 |
| Length: | 246 |
| Pfam Domains: | 6-128 'Paired box' domain 171-226 Homeobox domain |
| Sequence: (in bold interface residues) | 1 QQDGLSSVNQLGGLFVNGRPLPLDTRQQIVQLAIRGMRPCDISRSLKVSNGCVSKILGRY 60 61 YRTGVLEPKCIGGSKPRLATPAVVARIAQLKDEYPALFAWEIQHQLCTEGLCTQDKAPSV 120 121 SSINRVLRALQEDQSLHWTQLRSPAVLAPVLPSPHSNCGAPRGPHPGTSHRNRTIFSPGQ 180 181 AEALEKEFQRGQYPDSVARGKLAAATSLPEDTVRVWFSNRRAKWRRQEKLKWEAQLPGAS 240 241 QDLTVP |
| Interface Residues: | 17, 49, 50, 52, 54, 55, 71, 74, 77, 119, 120, 121, 122, 124, 125, 128, 156, 157, 158, 161, 162, 168, 170, 171, 172, 173, 211, 212, 214, 215, 218, 219, 222, 223, 226 |
| 3D-footprint Homologues: | 1pdn_C, 6pax_A, 1k78_A, 1au7_A, 1mnm_C, 1puf_A, 1fjl_B, 3d1n_M, 1jgg_B, 3lnq_A, 2lkx_A, 1nk2_P, 1zq3_P, 2ld5_A, 6es3_K, 7q3o_C, 3l1p_A, 5zjt_E, 3a01_E, 2h1k_B, 5hod_A, 6a8r_A, 3cmy_A, 2hdd_A, 7psx_B, 5jlw_D, 3rkq_B, 2r5y_A, 1puf_B, 1b72_A, 4xrs_G, 2hos_A, 1ig7_A, 5zfz_A, 4cyc_A, 6m3d_C, 5flv_I, 7xrc_C, 1e3o_C, 2xsd_C, 1le8_A, 8g87_X, 1k61_B, 4qtr_D, 1o4x_A, 1du0_A, 4j19_B |
| Binding Motifs: | UP00247A_1 wsawyTAATTAryysdm |
| Binding Sites: | AAATTAAT AATTAATA AATTAATC AATTAATG AATTAATT AATTAGTG ACTAATTA ATAATTAA ATTAATTA CAAATTAA CCTAATTA CGAATTAA CTAATTAA CTTAATTA GCTAATTA GTAATTAC GTTAATTA TAATTAAA TAATTAGA TTAATTAA |
| Publications: | Berger M.F, Badis G, Gehrke A.R, Talukder S, Philippakis A.A, Peña-Castillo L, Alleyne T.M, Mnaimneh S, Botvinnik O.B, Chan E.T, Khalid F, Zhang W, Newburger D, Jaeger S.A, Morris Q.D, Bulyk M.L, Hughes T.R. Variation in homeodomain DNA binding revealed by high-resolution analysis of sequence preferences. Cell 133:1266-76 (2008). [Pubmed] |
| Related annotations: | PaperBLAST |
Disclaimer and license
These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.