Transcription Factor

Accessions: UP00253A (UniPROBE 20160601)
Names: 7530406A22Rik, E130303K03Rik, ey-1, ey1, Rax, retina and anterior neural fold homeobox, Retina and anterior neural fold homeobox protein, Retinal homeobox protein Rx
Organisms: Mus musculus
Libraries: UniPROBE 20160601 1
1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed]
Uniprot: O35602
Description: retina and anterior neural fold homeobox
Length: 93
Pfam Domains: 17-73 Homeobox domain
Sequence:
(in bold interface residues)
1 AGDSKLSEEEPPKKKHRRNRTTFTTYQLHELERAFEKSHYPDVYSREELAGKVNLPEVRV 60
61 QVWFQNRRAKWRRQEKLEVSSMKLQDSPLLSFI
Interface Residues: 15, 17, 18, 19, 20, 58, 59, 61, 62, 65, 66, 69, 70, 73
3D-footprint Homologues: 3d1n_M, 1fjl_B, 5zfz_A, 1ig7_A, 2h1k_B, 1puf_A, 6a8r_A, 3cmy_A, 1nk2_P, 1zq3_P, 6m3d_C, 1jgg_B, 3lnq_A, 2lkx_A, 2ld5_A, 1puf_B, 6es3_K, 4xrs_G, 2hos_A, 1b72_A, 4cyc_A, 5flv_I, 3l1p_A, 5zjt_E, 4j19_B, 3a01_E, 7psx_B, 5hod_A, 2hdd_A, 7q3o_C, 1au7_A, 5jlw_D, 3rkq_B, 2r5y_A, 7xrc_C, 2xsd_C, 1e3o_C, 1le8_A, 1o4x_A, 8g87_X, 1du0_A, 4qtr_D
Binding Motifs: UP00253A_1 wscayYAATTRryssmy
Binding Sites: GGTAATTA
AATAATTA
ACCAATTA
ACTAATTA
ATAATTAG
ATTAATTA
CAATTAGC
CCAATTAA
CCAATTAG
CCTAATTA
CTAATTAA
CTAATTAC
CTTAATTA
GCCAATTA
GCTAATTA
GTAATTAA
GTTAATTA
TAATTAAA
TAATTAGA
TTAATTAA
Publications: Berger M.F, Badis G, Gehrke A.R, Talukder S, Philippakis A.A, Peña-Castillo L, Alleyne T.M, Mnaimneh S, Botvinnik O.B, Chan E.T, Khalid F, Zhang W, Newburger D, Jaeger S.A, Morris Q.D, Bulyk M.L, Hughes T.R. Variation in homeodomain DNA binding revealed by high-resolution analysis of sequence preferences. Cell 133:1266-76 (2008). [Pubmed]
Related annotations: PaperBLAST

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.