Transcription Factor

Accessions: UP00113A (UniPROBE 20160601)
Names: homeo box C4, Homeobox protein Hox-C4, Hox-3.5, Hoxc-4, Hoxc4
Organisms: Mus musculus
Libraries: UniPROBE 20160601 1
1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed]
Uniprot: Q08624
Description: homeo box C4
Length: 93
Pfam Domains: 17-73 Homeobox domain
Sequence:
(in bold interface residues)
1 KIHVSTVNPNYNGGEPKRSRTAYTRQQVLELEKEFHYNRYLTRRRRIEIAHSLCLSERQI 60
61 KIWFQNRRMKWKKDHRLPNTKVRSAPPAGAAPS
Interface Residues: 17, 18, 19, 20, 58, 59, 61, 62, 65, 66, 69, 70, 73
3D-footprint Homologues: 6a8r_A, 1fjl_B, 2h1k_B, 1puf_A, 3cmy_A, 5zfz_A, 3d1n_M, 3lnq_A, 2lkx_A, 6m3d_C, 1jgg_B, 1nk2_P, 1zq3_P, 2ld5_A, 3a01_E, 7q3o_C, 5jlw_D, 1b72_A, 6es3_K, 1ig7_A, 4xrs_G, 2hdd_A, 3rkq_B, 2r5y_A, 5flv_I, 2hos_A, 5zjt_E, 4cyc_A, 7psx_B, 5hod_A, 1le8_A, 7xrc_C, 1e3o_C, 2xsd_C, 1o4x_A, 4qtr_D, 1mnm_C, 1du0_A, 1puf_B, 8g87_X, 1k61_B, 3l1p_A
Binding Motifs: UP00113A_1 CgmrTTAATTAAywawm
Binding Sites: GGTAATTA
AATAATTA
ACTAATTA
ATAATTAA
ATAATTAG
ATAATTAT
ATCATTAA
ATTAATGA
ATTAATTA
ATTAATTG
CTAATTAA
CTAATTAG
CTTAATTA
GATAATTA
GCTAATTA
GTAATTAA
GTAATTAC
GTCATTAA
GTTAATTA
TAATTATA
Publications: Berger M.F, Badis G, Gehrke A.R, Talukder S, Philippakis A.A, Peña-Castillo L, Alleyne T.M, Mnaimneh S, Botvinnik O.B, Chan E.T, Khalid F, Zhang W, Newburger D, Jaeger S.A, Morris Q.D, Bulyk M.L, Hughes T.R. Variation in homeodomain DNA binding revealed by high-resolution analysis of sequence preferences. Cell 133:1266-76 (2008). [Pubmed]
Related annotations: PaperBLAST

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.