DNA Binding Site
| Accessions: | ACAGATGT (UniPROBE 20160601), MA1123.3.5 (JASPAR 2024), MA1472.3.11 (JASPAR 2024), MA1472.3.16 (JASPAR 2024), MA2170.1.12 (JASPAR 2024), MA2170.1.15 (JASPAR 2024), UN0733.1.1 (JASPAR 2024) |
| Organisms: | Caenorhabditis elegans, Homo sapiens, Mus musculus |
| Libraries: | UniPROBE 20160601 1, JASPAR 2024 2 1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed] 2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Length: | 8 |
| Sequence: | ACAGATGT |
| Type: | Heterodimer |
| Binding TFs: | UP00359A (Helix-loop-helix DNA-binding domain, Neuronal helix-loop-helix transcription factor ) UP00371A (Helix-loop-helix DNA-binding domain) UP00381A (Helix-loop-helix DNA-binding domain) UP00384A (Helix-loop-helix DNA-binding domain) Q9QYC3 (Helix-loop-helix DNA-binding domain) UP00548C (Helix-loop-helix DNA-binding domain) UP00548D (Helix-loop-helix DNA-binding domain) Q15672 (Helix-loop-helix DNA-binding domain) Q10574 Q11094 Q15672 Q9QYC3 |
| Binding Motifs: | UP00359A_1 wkdraaaaraastm UP00371A_1 wtaAAwaAAacymw UP00381A_1 akwraTwagwaswm UP00359A_2 / UP00384A_2 mskaACAkCTGTyyaa UP00371A_2 / UP00384A_9 aymaACATmTGGtwkm UP00381A_2 / UP00384A_10 hmgamCAgcTGkymtc UP00548C_1 rywgggRACAGCTGtyyksracm UP00548D_1 mrkrkrkRACAGcTGTymgrkmm MA1123.3 CCAGATGt MA1472.3 ACAGCTGT MA2170.1 ACAGrTGk UN0733.1 cCAGmTGg |
| Publications: | Grove C.A, De Masi F, Barrasa M.I, Newburger D.E, Alkema M.J, Bulyk M.L, Walhout A.J. A multiparameter network reveals extensive divergence between C. elegans bHLH transcription factors. Cell 138:314-27 (2009). [Pubmed] Shukunami C, Takimoto A, Nishizaki Y, Yoshimoto Y, Tanaka S, Miura S, Watanabe H, Sakuma T, Yamamoto T, Kondoh G, Hiraki Y. Scleraxis is a transcriptional activator that regulates the expression of Tenomodulin, a marker of mature tenocytes and ligamentocytes. Sci Rep 8:3155 (2018). [Pubmed] Lo HG, Jin RU, Sibbel G, Liu D, Karki A, Joens MS, Madison BB, Zhang B, Blanc V, Fitzpatrick JA, Davidson NO, Konieczny SF, Mills JC. A single transcription factor is sufficient to induce and maintain secretory cell architecture. Genes Dev 31:154-171 (2017). [Pubmed] Portman DS, Emmons SW. The basic helix-loop-helix transcription factors LIN-32 and HLH-2 function together in multiple steps of a C. elegans neuronal sublineage 127:5415-26 (Development.). [Pubmed] |
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